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Product Details
PA5-115173
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ELN(Accession P15502), corresponding to amino acid residues V597-G647.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2899809
Product Specific Information
Antibody detects endogenous levels of total Elastin.
Target Information
This gene encodes a protein that is one of the two components of elastic fibers. The encoded protein is rich in hydrophobic amino acids such as glycine and proline, which form mobile hydrophobic regions bounded by crosslinks between lysine residues. Deletions and mutations in this gene are associated with supravalvular aortic stenosis (SVAS) and autosomal dominant cutis laxa. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Elastin; FLJ38671; FLJ43523; Tropoelastin
Gene Aliases: AI385707; AI480567; E030024M20Rik; ELN; RATTREL11; SVAS; TREL11; Trela; Trela26; WBS; WS
UniProt ID: (Human) Q6ZWJ6, (Rat) Q99372, (Mouse) P54320
Entrez Gene ID: (Human) 2006, (Rat) 25043, (Mouse) 13717
respiratory gaseous exchange
blood circulation
cell proliferation
organ morphogenesis
extracellular matrix disassembly
extracellular matrix organization
blood vessel remodeling
skeletal muscle tissue development
aging
regulation of actin filament polymerization
aorta development
response to diuretic
stress fiber assembly
cellular response to fibroblast growth factor stimulus
elastic fiber assembly
response to hyperoxia
cellular response to copper ion
cellular response to L-ascorbic acid
cellular response to retinoic acid
cellular response to organic cyclic compound
cellular response to hypoxia
cellular response to dexamethasone stimulus
cellular response to transforming growth factor beta stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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