Product References
RIT1 regulation of CNS lipids RIT1 deficiency Alters cerebral lipid metabolism and reduces white matter tract oligodendrocytes and conduction velocities.
Heliyon
Wu L,Wang F,Moncman CL,Pandey M,Clarke HA,Frazier HN,Young LEA,Gentry MS,Cai W,Thibault O,Sun RC,Andres DA
MA3-005 was used in Western Blot to reveal an unexpected role for RIT1 in the regulation of cerebral lipid metabolism, which coincide with altered white matter tract oligodendrocyte levels, reduced axonal conduction velocity, and behavioral abnormalities in the CNS.
Sun Oct 01 00:00:00 EDT 2023
Robust generation of human-chambered cardiac organoids from pluripotent stem cells for improved modelling of cardiovascular diseases.
Stem cell research & therapy
Ho BX,Pang JKS,Chen Y,Loh YH,An O,Yang HH,Seshachalam VP,Koh JLY,Chan WK,Ng SY,Soh BS
MA3-005 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Radioimmune assays, Western Blot to demonstrate that a threshold number of cardiac progenitor was essential to line the circumference of the inner cavity to ensure proper formation of a chamber within the organoid.
Wed Dec 21 00:00:00 EST 2022
Inhibition of p38 MAPK Mitigates Lung Ischemia Reperfusion Injury by Reducing Blood-Air Barrier Hyperpermeability.
Frontiers in pharmacology
Wang T,Liu C,Pan LH,Liu Z,Li CL,Lin JY,He Y,Xiao JY,Wu S,Qin Y,Li Z,Lin F
MA3-005 was used in Western Blotting to study the inhibition of p38 MAPK which alleviates LIRI by decreasing blood-air hyperpermeability.
Tue Dec 29 00:00:00 EST 2020
Inhibition of p38 MAPK Mitigates Lung Ischemia Reperfusion Injury by Reducing Blood-Air Barrier Hyperpermeability.
Frontiers in pharmacology
Wang T,Liu C,Pan LH,Liu Z,Li CL,Lin JY,He Y,Xiao JY,Wu S,Qin Y,Li Z,Lin F
MA3-005 was used in Western Blotting to study the inhibition of p38 MAPK which alleviates LIRI by decreasing blood-air hyperpermeability.
Tue Dec 29 00:00:00 EST 2020
The Endothelin Receptor Antagonist Macitentan Improves Isosorbide-5-Mononitrate (ISMN) and Isosorbide Dinitrate (ISDN) Induced Endothelial Dysfunction, Oxidative Stress, and Vascular Inflammation.
Oxidative medicine and cellular longevity
Steven S,Oelze M,Hausding M,Roohani S,Kashani F,Kröller-Schön S,Helmstädter J,Jansen T,Baum C,Iglarz M,Schulz E,Münzel T,Daiber A
MA3-005 was used in Immunohistochemistry to test the therapeutic effects of the dual endothelin receptor antagonist macitentan in isosorbide-5-mononitrate and isosorbide dinitrate-treated animals.
Tue Feb 19 00:00:00 EST 2019
Antenatal Saireito (TJ-114) Can Improve Pulmonary Hypoplasia and Pulmonary Vascular Remodeling in Nitrofen-Induced Congenital Diaphragmatic Hernia.
Phytotherapy research : PTR
Hirako S,Tsuda H,Kotani T,Sumigama S,Mano Y,Nakano T,Imai K,Li H,Toyokuni S,Kikkawa F
MA3005 was used in immunohistochemistry - paraffin section to determine the efficacy and safety of antenatal Saireito in a rat congenital diaphragmatic hernia model
Thu Sep 01 00:00:00 EDT 2016
Immature endothelial cells initiate endothelin-mediated constriction of newborn arteries.
The Journal of physiology
Chang F,Flavahan S,Flavahan NA
MA3005 was used in immunohistochemistry to show that endothelial cells lining newborn central arteries express high levels of ET-1 peptides and examine the release of ET-1 peptides from these cells
Thu Sep 01 00:00:00 EDT 2016
Characterization of osteoblastic and osteolytic proteins in prostate cancer bone metastases.
The Prostate
Larson SR,Zhang X,Dumpit R,Coleman I,Lakely B,Roudier M,Higano CS,True LD,Lange PH,Montgomery B,Corey E,Nelson PS,Vessella RL,Morrissey C
MA3-005 was used in immunohistochemistry to characterize osteoblastic and osteolytic proteins in prostate cancer bone metastases
Sat Jun 01 00:00:00 EDT 2013
Cellular, pharmacological, and biophysical evaluation of explanted lungs from a patient with sickle cell disease and severe pulmonary arterial hypertension.
Pulmonary circulation
Rogers NM,Yao M,Sembrat J,George MP,Knupp H,Ross M,Sharifi-Sanjani M,Milosevic J,St Croix C,Rajkumar R,Frid MG,Hunter KS,Mazzaro L,Novelli EM,Stenmark KR,Gladwin MT,Ahmad F,Champion HC,Isenberg JS
MA3-005 was used in Immunohistochemistry to evaluate the molecular, cellular, functional, and mechanical changes in end-stage sickle cell disease-associated pulmonary arterial hypertension.
Sun Dec 01 00:00:00 EST 2013
Effect of raloxifene and atorvastatin in atherosclerotic process in ovariectomized rats.
The journal of obstetrics and gynaecology research
Cetinkaya Demir B,Uyar Y,Ozbilgin K,Köse C
Published figure using Endothelin 1 monoclonal antibody (Product # MA3-005) in Immunohistochemistry
Tue Jan 01 00:00:00 EST 2013
Effect of raloxifene and atorvastatin in atherosclerotic process in ovariectomized rats.
The journal of obstetrics and gynaecology research
Cetinkaya Demir B,Uyar Y,Ozbilgin K,Köse C
Published figure using Endothelin 1 monoclonal antibody (Product # MA3-005) in Immunohistochemistry
Tue Jan 01 00:00:00 EST 2013
Endothelin-1 enriched tumor phenotype predicts breast cancer recurrence.
ISRN oncology
Tamkus D,Sikorskii A,Gallo KA,Wiese DA,Leece C,Madhukar BV,Chivu SC,Chitneni S,Dimitrov NV
MA3-005 was used in immunohistochemistry to study the utility of endothelin-1 expression in tumor and stromal tissue for predicting breast cancer recurrence
Thu Jul 11 00:00:00 EDT 2013
Decompression of the portal bed and twice-baseline portal inflow are necessary for the functional recovery of a "small-for-size" graft.
Annals of surgery
Hessheimer AJ,Fondevila C,Taurá P,Muñoz J,Sánchez O,Fuster J,Rimola A,García-Valdecasas JC
MA3-005 was used in immunohistochemistry to investigate the effect of a calibrated portocaval shunt on superfluous inflow in a porcine model of small-for-size syndrome
Wed Jun 01 00:00:00 EDT 2011
Decompression of the portal bed and twice-baseline portal inflow are necessary for the functional recovery of a "small-for-size" graft.
Annals of surgery
Hessheimer AJ,Fondevila C,Taurá P,Muñoz J,Sánchez O,Fuster J,Rimola A,García-Valdecasas JC
MA3-005 was used in immunohistochemistry to investigate the effect of a calibrated portocaval shunt on superfluous inflow in a porcine model of small-for-size syndrome
Wed Jun 01 00:00:00 EDT 2011
Rescue treatment with a Rho-kinase inhibitor normalizes right ventricular function and reverses remodeling in juvenile rats with chronic pulmonary hypertension.
American journal of physiology. Heart and circulatory physiology
Xu EZ,Kantores C,Ivanovska J,Engelberts D,Kavanagh BP,McNamara PJ,Jankov RP
MA3-005 was used in western blot to investigate the effect of ROCK inhibition on chronic pulmonary hypertension in rats
Wed Dec 01 00:00:00 EST 2010
Clinicopathologic efficacy of copper bromide plus/yellow laser (578 nm with 511 nm) for treatment of melasma in Asian patients.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
Lee HI,Lim YY,Kim BJ,Kim MN,Min HJ,Hwang JH,Song KY
MA3-005 was used in immunohistochemistry to investigate the efficiency of laser treatment on melasma in Asians
Tue Jun 01 00:00:00 EDT 2010
CXCR6, a newly defined biomarker of tissue-specific stem cell asymmetric self-renewal, identifies more aggressive human melanoma cancer stem cells.
PloS one
Taghizadeh R,Noh M,Huh YH,Ciusani E,Sigalotti L,Maio M,Arosio B,Nicotra MR,Natali P,Sherley JL,La Porta CA
MA3-005 was used in immunohistochemistry to study CXCR6 as a marker of more aggressive human melanoma cancer stem cells
Wed Dec 22 00:00:00 EST 2010
Endothelin-1 expression correlates with atypical histological features in mammary phyllodes tumours.
Journal of clinical pathology
Tse GM,Chaiwun B,Lau KM,Scolyer R,Lee CS,Karim RZ,Putti TC,Law BK,Lui PC,Tan PH
MA3-005 was used in immunohistochemistry to study the correlation between endothelin-1 expression and atypical histological features in mammary phyllodes tumors
Sat Sep 01 00:00:00 EDT 2007
Significance of enhanced expression of nitric oxide syntheses in splenic sinus lining cells in altered portal hemodynamics of idiopathic portal hypertension.
Digestive diseases and sciences
Sato Y,Sawada S,Kozaka K,Harada K,Sasaki M,Matsui O,Nakanuma Y
MA3-005 was used in immunohistochemistry to study the significance of enhanced expression of splenic sinus nitric oxide synthase in idiopathic portal hypertension
Wed Aug 01 00:00:00 EDT 2007
The human placenta from heavy smokers: evaluation of vasoactive peptides by immunohistochemistry.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
Clausen HV,Larsen LG,Jørgensen A,Bzorek M
MA3-005 was used in immunohistochemistry to investigate the expression of e-NOS and endothelin-1 in human placenta from heavy smokers and non-smokers
Mon Jan 01 00:00:00 EST 2007
Comprehensive immunohistological analysis of the endothelin system in human kidney grafts.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Frank K,Zeier M,Gross ML,Waldherr R,Ritz E,Amann K
MA3-005 was used in immunohistochemistry to investigate the expression of endothelin (ET)-1, ET-RA and ET-RB in the different cells and compartments of kidney grafts
Mon May 01 00:00:00 EDT 2006
Green tea polyphenol epigallocatechin-3-gallate inhibits the endothelin axis and downstream signaling pathways in ovarian carcinoma.
Molecular cancer therapeutics
Spinella F,Rosanò L,Di Castro V,Decandia S,Albini A,Nicotra MR,Natali PG,Bagnato A
MA3-005 was used in western blot to study the inhibitory effect of epigallocatechin-3-gallate on endothelin signaling pathways in ovarian carcinoma
Thu Jun 01 00:00:00 EDT 2006
Expression of the endothelin axis in bladder cancer: relationship to clinicopathologic parameters and long-term survival.
European urology
Wülfing C,Eltze E,Yamini J,Wülfing P,Bierer S,Böcker W,Hertle L,Semjonow A,Sievert KD
MA3-005 was used in immunohistochemistry to study the role of the endothelin axis in bladder cancer
Sun May 01 00:00:00 EDT 2005
Endothelin-1 promotes epithelial-to-mesenchymal transition in human ovarian cancer cells.
Cancer research
Rosanò L,Spinella F,Di Castro V,Nicotra MR,Dedhar S,de Herreros AG,Natali PG,Bagnato A
MA3-005 was used in immunohistochemistry to study the role of endothelin-1 in promoting epithelial-to-mesenchymal transition in human ovarian cancer cells
Thu Dec 15 00:00:00 EST 2005
Endothelial alterations during inhaled NO in lambs with pulmonary hypertension: implications for rebound hypertension.
American journal of physiology. Lung cellular and molecular physiology
Ross GA,Oishi P,Azakie A,Fratz S,Fitzgerald RK,Johengen MJ,Harmon C,Hendricks-Munoz K,Xu J,Black SM,Fineman JR
MA3-005 was used in western blot to suggest that the endothelial response to iNO and the potential mechanisms of rebound pulmonary hypertension are dependent upon the underlying pulmonary vasculature
Sat Jan 01 00:00:00 EST 2005
Developmental changes in endothelial vasoactive and angiogenic growth factors in the human perinatal lung.
Pediatric research
Levy M,Maurey C,Chailley-Heu B,Martinovic J,Jaubert F,Israel-Biet D
MA3-005 was used in immunohistochemistry to investigate the expression of endothelial vasoactive and angiogenic growth factors during human perinatal lung development
Tue Feb 01 00:00:00 EST 2005
Ouabain stimulates endothelin release and expression in human endothelial cells without inhibiting the sodium pump.
European journal of biochemistry
Saunders R,Scheiner-Bobis G
MA3-005 was used in western blot to investigate the effect of ouabain on ET-1 expression and release in human endothelial cells
Mon Mar 01 00:00:00 EST 2004
Emergence of smooth muscle cell endothelin B-mediated vasoconstriction in lambs with experimental congenital heart disease and increased pulmonary blood flow.
Circulation
Black SM,Mata-Greenwood E,Dettman RW,Ovadia B,Fitzgerald RK,Reinhartz O,Thelitz S,Steinhorn RH,Gerrets R,Hendricks-Munoz K,Ross GA,Bekker JM,Johengen MJ,Fineman JR
MA3-005 was used in western blot to investigate the role of ETB receptors in the pathophysiology of pulmonary hypertension in lambs with experimental congenital heart disease and increased pulmonary blood flow
Tue Sep 30 00:00:00 EDT 2003
Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization.
The Journal of clinical investigation
Kondo T,Vicent D,Suzuma K,Yanagisawa M,King GL,Holzenberger M,Kahn CR
MA3-005 was used in immunohistochemistry to study the role of insulin and IGF-1 signaling in retinal neovascularization.
Sun Jun 01 00:00:00 EDT 2003
Endothelin-1 and macrophage colony-stimulating factor are co-localized in human amnion membrane cells and secreted into amniotic fluid.
Molecular human reproduction
Fried G,Sand A,Ostlund E,Andersson E,Byström B,Ståbi B
MA3-005 was used in immunohistochemistry to investigate the localization of endothelin-1 and macrophage colony-stimulating factor in human amnion membrane cells
Sat Nov 01 00:00:00 EST 2003
Nitric oxide-endothelin-1 interactions after acute ductal constriction in fetal lambs.
American journal of physiology. Heart and circulatory physiology
Ovadia B,Bekker JM,Fitzgerald RK,Kon A,Thelitz S,Johengen MJ,Hendricks-Munoz K,Gerrets R,Black SM,Fineman JR
MA3-005 was used in western blot to investigate the role of NO-ET-1 interactions in fetal pulmonary blood flow after acute mechanical constriction of the ductus arteriosus
Fri Mar 01 00:00:00 EST 2002
Expression and regulation of endothelin-1 and its receptors in human penile smooth muscle cells.
Molecular human reproduction
Granchi S,Vannelli GB,Vignozzi L,Crescioli C,Ferruzzi P,Mancina R,Vinci MC,Forti G,Filippi S,Luconi M,Ledda F,Maggi M
MA3-005 was used in immunohistochemistry to study the expression of ET-1 and corresponding regulation and to identify its receptors in the human penis
Sun Dec 01 00:00:00 EST 2002
Use of in vitro organ cultures of human saphenous vein as a model for intimal proliferation.
Methods in molecular biology (Clifton, N.J.)
Porter KE
MA3-005 was used in immunohistochemistry to generate organ cultures of human long saphenous vein for the study of intimal hyperplasia
Fri Aug 01 00:00:00 EDT 2003
Pathogenic role of endothelin 1 in hemodynamic dysfunction in experimental acute pulmonary thromboembolism.
American journal of respiratory and critical care medicine
Lee JH,Chun YG,Lee IC,Tuder RM,Hong SB,Shim TS,Lim CM,Koh Y,Kim WS,Kim DS,Kim WD,Lee SD
MA3-005 was used in immunohistochemistry to investigate the role of endothelin 1 in hemodynamic derangements of acute pulmonary thromboembolism
Mon Oct 01 00:00:00 EDT 2001
Endothelin receptor blockade inhibits proliferation of Kaposi's sarcoma cells.
The American journal of pathology
Bagnato A,Rosanò L,Di Castro V,Albini A,Salani D,Varmi M,Nicotra MR,Natali PG
MA3-005 was used in immunohistochemistry to investigate the impact of the endothelin receptor blockade on Kaposi's sarcoma cells.
Thu Mar 01 00:00:00 EST 2001
Inhaled nitric oxide-induced rebound pulmonary hypertension: role for endothelin-1.
American journal of physiology. Heart and circulatory physiology
McMullan DM,Bekker JM,Johengen MJ,Hendricks-Munoz K,Gerrets R,Black SM,Fineman JR
MA3-005 was used in western blot to investigate the role of endothelin-1 in the inhaled nitric oxide-induced rebound pulmonary hypertension
Thu Feb 01 00:00:00 EST 2001
Vascular remodeling and ET-1 expression in rat strains with different responses to chronic hypoxia.
American journal of physiology. Lung cellular and molecular physiology
Aguirre JI,Morrell NW,Long L,Clift P,Upton PD,Polak JM,Wilkins MR
MA3-005 was used in immunohistochemistry to investigate the vascular remodeling and expression of endothelin-1 in rat
Mon May 01 00:00:00 EDT 2000
Role of endothelin-1 in neovascularization of ovarian carcinoma.
The American journal of pathology
Salani D,Di Castro V,Nicotra MR,Rosanò L,Tecce R,Venuti A,Natali PG,Bagnato A
MA3-005 was used in immunohistochemistry to study the role of endothelin 1 in ovarian cancer related-angiogenesis and its potential as a target of anti-angiogenic therapy.
Wed Nov 01 00:00:00 EST 2000
Expression of endothelin 1 and endothelin A receptor in ovarian carcinoma: evidence for an autocrine role in tumor growth.
Cancer research
Bagnato A,Salani D,Di Castro V,Wu-Wong JR,Tecce R,Nicotra MR,Venuti A,Natali PG
MA3-005 was used in immunohistochemistry to study the endothelin 1 and the ETA receptor expression in primary and metastatic ovarian carcinomas and their involvement in tumor growth.
Mon Feb 01 00:00:00 EST 1999
Gene expression of endothelin-1, endothelin-converting enzyme-1, and endothelin receptors in human epididymis.
The Journal of clinical endocrinology and metabolism
Peri A,Fantoni G,Granchi S,Vannelli GB,Barni T,Amerini S,Pupilli C,Barbagli G,Forti G,Serio M,Maggi M
MA3-005 was used in immunohistochemistry to detect the expression of ET-1 in the human epididymis
Sat Nov 01 00:00:00 EST 1997
Endothelin-1 production and decreased endothelin B receptor expression in advanced prostate cancer.
Cancer research
Nelson JB,Chan-Tack K,Hedican SP,Magnuson SR,Opgenorth TJ,Bova GS,Simons JW
MA3-005 was used in immunohistochemistry to detect the expression of endothelin-1 (ET-l) in advanced prostate cancer
Thu Feb 15 00:00:00 EST 1996
Endothelin: localization, synthesis, activity, and receptor types in human penile corpus cavernosum.
The American journal of physiology
Saenz de Tejada I,Carson MP,de las Morenas A,Goldstein I,Traish AM
MA3-005 was used in immunocytochemistry to investigate the roles of endothelin in the regulation of human penile smooth muscle
Tue Oct 01 00:00:00 EDT 1991