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For neutralization, use at a concentration of 7-8 µg/mL to achieve half of the neutralizing dose (ND50) of a 100.0 ng/mL concentration.
Eotaxin 2 belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line.
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Protein Aliases: C-C motif chemokine 24; CC chemokine CCL24; Eosinophil chemotactic protein 2; Eotaxin-2; Eotaxin2; small inducible cytokine A24; Small-inducible cytokine A24
Gene Aliases: Ccl24; CKb-6; MPIF-2; Scya24
UniProt ID: (Mouse) Q9JKC0
Entrez Gene ID: (Mouse) 56221
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