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Eotaxin 2 Antibody (MA5-23851) in Neu
Neutralization of Eotaxin 2 in BaF3 mouse pro‚B cell line transfected with mouse CCR3. Samples were incubated in Eotaxin 2 monoclonal antibody (Product # MA5-23851). Recombinant Mouse CCL24/Eotaxin‚2 chemoattracts the BaF3 mouse pro‚B cell line transfected with mouse CCR3 in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin. Chemotaxis elicited by Recombinant Mouse CCL24/Eotaxin‚2 (20 ng/mL) is neutralized (green line) by increasing concentrations of R... View More
Product Details
MA5-23851
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rat
/ IgG2A
Class
Monoclonal
Type
Antibody
Clone
106521
Immunogen
E. coli-derived recombinant mouse CCL24/Eotaxin-2/MPIF-2 Ile24-Val119
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2577145
Product Specific Information
Reconstitute at 0.5 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
Eotaxin 2 belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C-C motif chemokine 24; CC chemokine CCL24; Eosinophil chemotactic protein 2; Eotaxin-2; Eotaxin2; small inducible cytokine A24; Small-inducible cytokine A24
Gene Aliases: Ccl24; CKb-6; MPIF-2; Scya24
UniProt ID: (Mouse) Q9JKC0
Entrez Gene ID: (Mouse) 56221
positive regulation of endothelial cell proliferation
chemotaxis
inflammatory response
immune response
cytoskeleton organization
regulation of cell shape
positive regulation of cell migration
positive regulation of actin filament polymerization
positive regulation of GTPase activity
positive regulation of angiogenesis
eosinophil chemotaxis
positive regulation of inflammatory response
positive regulation of eosinophil migration
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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