Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
MA1-24653
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
61016.11
Immunogen
Purified, recombinant human eotaxin 2, expressed in E. coli.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_780462
Product Specific Information
The Neutralization Dose50 (ND50) for this antibody is approximately 1 to 5 µg/mL in the presence of 100 ng/mL of recombinant human eotaxin 2, measuring the chemotaxis of rat myeloid Y3 cells transfected with the human CCR3 gene.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Eotaxin 2 belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: C-C motif chemokine 24; chemokine (C-C motif) ligand 24; CK-beta-6; Eosinophil chemotactic protein 2; Eotaxin-2; Eotaxin2; MPIF-2; Myeloid progenitor inhibitory factor 2; small inducible cytokine subfamily A (Cys-Cys), member 24; Small-inducible cytokine A24
Gene Aliases: CCL24; Ckb-6; MPIF-2; MPIF2; SCYA24
UniProt ID: (Human) O00175
Entrez Gene ID: (Human) 6369
positive regulation of endothelial cell proliferation
monocyte chemotaxis
chemotaxis
inflammatory response
immune response
cytoskeleton organization
signal transduction
G-protein coupled receptor signaling pathway
cell-cell signaling
regulation of cell shape
positive regulation of cell migration
neutrophil chemotaxis
positive regulation of actin filament polymerization
positive regulation of GTPase activity
positive regulation of angiogenesis
eosinophil chemotaxis
lymphocyte chemotaxis
positive regulation of inflammatory response
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
positive regulation of eosinophil migration
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support