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Product Details
MA5-15448
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
9A12D8
Immunogen
Purified recombinant fragment of EphA8 (aa70-150) expressed in E. Coli.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
ascites
Contains
0.03% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_11000213
Product Specific Information
MA5-15448 targets EphA8 in indirect ELISA, WB applications and shows reactivity with Human samples.
The MA5-15448 immunogen is purified recombinant fragment of EphA8 (aa70-150) expressed in E. Coli.
Target Information
EPHA8 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. EPHA8 plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EK3; epa8; EPH- and ELK-related kinase; EPH- and ELK-related tyrosine kinase; EPH-like kinase 3; Ephrin type-A receptor 8; hydroxyaryl-protein kinase; protein-tyrosine kinase; Tyrosine-protein kinase receptor EEK; tyrosylprotein kinase
Gene Aliases: EEK; EK3; EPHA8; HEK3; KIAA1459
UniProt ID: (Human) P29322
Entrez Gene ID: (Human) 2046
substrate-dependent cell migration
cell adhesion
axon guidance
neuron remodeling
peptidyl-tyrosine phosphorylation
regulation of cell adhesion
neuron projection development
regulation of cell adhesion mediated by integrin
positive regulation of MAPK cascade
positive regulation of phosphatidylinositol 3-kinase activity
protein autophosphorylation
ephrin receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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