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Product Details
PA5-81557
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to the center region of the Mouse EphB2/Eph Receptor B2
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2788759
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Mouse EphB2.
Target Information
EPHB2 is a receptor tyrosine kinase that belongs to the ephrin receptor family. Members of the Eph family of kinases play important roles in diverse biological processes including nervous system development, angiogenesis and neural synapsis formation and maturation. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EFL6; EFNB3; EPH B2; EPHB3; Ephrin B1; Ephrin B2; Ephrin B3; Ephrin B4; Ephrin type-B receptor 2; EphrinB1; EphrinB2; EphrinB3; EphrinB4; EPLG8; ETK2; HEK-6; HEK2; LERK8; MGC87492; Neural kinase; Nuk receptor tyrosine kinase; TYRO6; Tyrosine-protein kinase receptor EPH-3; Tyrosine-protein kinase receptor SEK-3
Gene Aliases: Cek5; Drt; Ephb2; Epth3; Erk; ETECK; Hek5; Nuk; Prkm5; Qek5; Sek3; Tyro5
UniProt ID: (Mouse) Q6GTQ7
Entrez Gene ID: (Mouse) 13844
nucleotide binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
receptor activity
ephrin receptor activity
transmembrane-ephrin receptor activity
receptor binding
protein binding
ATP binding
axon guidance receptor activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
identical protein binding
transmembrane signal receptor
cell morphogenesis
angiogenesis
urogenital system development
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
multicellular organism development
nervous system development
axon guidance
axonal fasciculation
learning
organ morphogenesis
phosphorylation
peptidyl-tyrosine phosphorylation
optic nerve morphogenesis
central nervous system projection neuron axonogenesis
corpus callosum development
retinal ganglion cell axon guidance
inner ear morphogenesis
ephrin receptor signaling pathway
regulation of neuronal synaptic plasticity
positive regulation of long-term neuronal synaptic plasticity
camera-type eye morphogenesis
regulation of axonogenesis
negative regulation of axonogenesis
regulation of body fluid levels
positive regulation of synapse assembly
palate development
dendritic spine development
dendritic spine morphogenesis
commissural neuron axon guidance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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