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Product Details
PA5-112414
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Ephrin type-B receptor 3 protein (261-390AA)
Conjugate
Form
Liquid
Concentration
2.89 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_2867149
Target Information
EPHB3 is a receptor tyrosine kinase that belongs to the ephrin receptor family. Members of the Eph family of kinases play important roles in diverse biological processes including nervous system development, angiogenesis and neural synapsis formation and maturation. The ephrin ligands and Eph receptors display reciprocal expression in vivo. Developing and adult neural tissue express nearly all of the Eph receptors and ephrin ligands. Ephs and ephrins play a significant role in angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Developmental kinase 5; EK2; Embryonic kinase 2; EPH-like kinase 2; EPH-like tyrosine kinase 2; EPH-like tyrosine kinase-2; Ephrin type-B receptor 3; human embryo kinase 2; mDK-5; Tyrosine-protein kinase receptor SEK-4; Tyrosine-protein kinase TYRO6
Gene Aliases: AW456895; Cek10; EK2; EPHB3; ETK2; HEK2; MDK5; Sek4; TYRO6
UniProt ID: (Human) P54753, (Mouse) P54754
Entrez Gene ID: (Human) 2049, (Mouse) 13845, (Rat) 287989
ephrin receptor activity
ATP binding
axon guidance receptor activity
nucleotide binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
transmembrane-ephrin receptor activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
transmembrane signal receptor
angiogenesis
urogenital system development
axon guidance
axonal fasciculation
cell migration
peptidyl-tyrosine phosphorylation
central nervous system projection neuron axonogenesis
corpus callosum development
regulation of cell-cell adhesion
retinal ganglion cell axon guidance
substrate adhesion-dependent cell spreading
regulation of GTPase activity
protein autophosphorylation
ephrin receptor signaling pathway
thymus development
digestive tract morphogenesis
regulation of axonogenesis
positive regulation of synapse assembly
palate development
dendritic spine development
dendritic spine morphogenesis
protein phosphorylation
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
multicellular organism development
nervous system development
phosphorylation
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