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Product Details
PA5-80591
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human EPHB3/HEK2 protein
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2787889
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human EPHB3/HEK2.
Target Information
EPHB3 is a receptor tyrosine kinase that belongs to the ephrin receptor family. Members of the Eph family of kinases play important roles in diverse biological processes including nervous system development, angiogenesis and neural synapsis formation and maturation. The ephrin ligands and Eph receptors display reciprocal expression in vivo. Developing and adult neural tissue express nearly all of the Eph receptors and ephrin ligands. Ephs and ephrins play a significant role in angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EK2; Embryonic kinase 2; EPH-like kinase 2; EPH-like tyrosine kinase 2; Ephrin type-B receptor 3; human embryo kinase 2; Tyrosine-protein kinase TYRO6
Gene Aliases: EK2; EPHB3; ETK2; HEK2; TYRO6
UniProt ID: (Human) P54753
Entrez Gene ID: (Human) 2049
angiogenesis
urogenital system development
axon guidance
axonal fasciculation
cell migration
peptidyl-tyrosine phosphorylation
central nervous system projection neuron axonogenesis
corpus callosum development
regulation of cell-cell adhesion
retinal ganglion cell axon guidance
substrate adhesion-dependent cell spreading
regulation of GTPase activity
protein autophosphorylation
ephrin receptor signaling pathway
thymus development
digestive tract morphogenesis
regulation of axonogenesis
positive regulation of synapse assembly
palate development
dendritic spine development
dendritic spine morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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