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Product Details
MA5-31122
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
115
Immunogen
Recombinant Mouse EphB3/HEK2 protein (Met1-Thr537)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2786772
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Mouse EphB3/HEK2.
Target Information
EPHB3 is a receptor tyrosine kinase that belongs to the ephrin receptor family. Members of the Eph family of kinases play important roles in diverse biological processes including nervous system development, angiogenesis and neural synapsis formation and maturation. The ephrin ligands and Eph receptors display reciprocal expression in vivo. Developing and adult neural tissue express nearly all of the Eph receptors and ephrin ligands. Ephs and ephrins play a significant role in angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Developmental kinase 5; Ephrin type-B receptor 3; mDK-5; Tyrosine-protein kinase receptor SEK-4
Gene Aliases: AW456895; Cek10; Ephb3; Etk2; HEK2; MDK5; Sek4; Tyro6
UniProt ID: (Mouse) P54754
Entrez Gene ID: (Mouse) 13845
nucleotide binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
ephrin receptor activity
transmembrane-ephrin receptor activity
ATP binding
axon guidance receptor activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
transmembrane signal receptor
angiogenesis
urogenital system development
protein phosphorylation
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
multicellular organism development
nervous system development
axon guidance
axonal fasciculation
phosphorylation
cell migration
peptidyl-tyrosine phosphorylation
central nervous system projection neuron axonogenesis
corpus callosum development
regulation of cell-cell adhesion
retinal ganglion cell axon guidance
substrate adhesion-dependent cell spreading
regulation of GTPase activity
protein autophosphorylation
ephrin receptor signaling pathway
thymus development
digestive tract morphogenesis
regulation of axonogenesis
positive regulation of synapse assembly
palate development
dendritic spine development
dendritic spine morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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