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Product Details
EPHAR1-FITC
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 55-605 on human Ephrin type-A receptor 1.
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
EphA1 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EphA1 is expressed in some human cancer cell lines and has been implicated in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EPH tyrosine kinase; EPH tyrosine kinase 1; Ephrin type-A receptor 1; erythropoietin-producing hepatoma amplified sequence; Erythropoietin-producing hepatoma receptor; hEpha1; MGC163163; oncogene EPH; soluble EPHA1 variant 1; soluble EPHA1 variant 2; Tyrosine-protein kinase receptor EPH
Gene Aliases: EPH; EPHA1; EPHT; EPHT1
UniProt ID: (Human) P21709
Entrez Gene ID: (Human) 2041
angiogenesis
positive regulation of cell-matrix adhesion
negative regulation of protein kinase activity
cell surface receptor signaling pathway
positive regulation of cell proliferation
peptidyl-tyrosine phosphorylation
positive regulation of cell migration
negative regulation of cell migration
substrate adhesion-dependent cell spreading
somatic stem cell population maintenance
regulation of GTPase activity
positive regulation of angiogenesis
protein autophosphorylation
ephrin receptor signaling pathway
positive regulation of stress fiber assembly
activation of GTPase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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