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Invitrogen
Epstein Barr Virus Nuclear Antigen 1 Polyclonal Antibody, HRP
Product Details
PA1-7498
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Virus
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Purified recombinant EBV EBNA-1.
Conjugate
Form
Liquid
Concentration
1-2 mg/mL
Purification
IgG fraction
Storage buffer
PBS with 10mg/mL BSA
Contains
0.002% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_1017066
Product Specific Information
The PA1-7498 antibody reacts with Epstein-Barr virus EBNA-1.
PA1-7498 has been successfully used in ELISA applications.
The PA1-7498 antibody was raised against Recombinant EBV EBNA-1.
Note: Sodium azide is a potent inhibitor of peroxidase.
Target Information
Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EBNA-1
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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