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Product Details
PA5-68480
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human FA2H [aa 101-150].
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2692072
Product Specific Information
Predicted to react with Human and Rat samples.
Target Information
FA2H is a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Fatty acid 2-hydroxylase; Fatty acid alpha-hydroxylase; fatty acid hydroxylase domain containing 1; Fatty acid hydroxylase domain-containing protein 1; FLJ25287; spastic paraplegia 35 (autosomal recessive); WD repeat domain 59
Gene Aliases: FA2H; FAAH; FAH1; FAXDC1; G630055L08Rik; RGD1310347; SCS7; SPG35; Wdr59
UniProt ID: (Human) Q7L5A8, (Rat) Q2LAM0, (Mouse) Q5MPP0
Entrez Gene ID: (Human) 79152, (Rat) 307855, (Mouse) 338521
iron ion binding
heme binding
fatty acid alpha-hydroxylase activity
N-ethylmaleimide reductase activity
oxidoreductase activity
reduced coenzyme F420 dehydrogenase activity
sulfur oxygenase reductase activity
malolactic enzyme activity
NADPH:sulfur oxidoreductase activity
metal ion binding
epoxyqueuosine reductase activity
hydroxylase
sebaceous gland cell differentiation
fatty acid metabolic process
fatty acid biosynthetic process
sphingolipid biosynthetic process
lipid modification
central nervous system myelin maintenance
peripheral nervous system myelin maintenance
regulation of cell proliferation
regulation of hair cycle
oxidation-reduction process
sphingolipid metabolic process
lipid metabolic process
transport
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