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FABP3 Antibody (MA5-27875) in IHC (P)
Immunohistochemistry analysis of FABP3 on paraffin-embedded rat cardiac muscle tissue. Antigen retrieval was performed using citrate buffer (pH6, epitope retrieval solution) for 20 mins. Sample was blocked using 10% goat serum, incubated with FABP3 polyclonal antibody (Product# MA5-27875) with a dilution of 2 µg/mL (overnight at 4°C), followed by biotinylated goat anti-rabbit IgG (30 minutes at 37°C). Devel... View More
Product Details
MA5-27875
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
6C4
Immunogen
E. coli-derived rat Cardiac FABP recombinant protein (Position: A2-A133).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2744931
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Fatty acid binding proteins (FABP) are small (approximately 13-14 kDa) intracellular proteins with a high degree of tissue specificity. FABPs are a class of cytoplasmic proteins that bind long chain fatty acids. They are abundantly present in various cell types and seem to play an important role in the intracellular utilization of fatty acids. There are at least six distinct types of FABP, each showing a specific pattern of tissue expression. FABP leaks, due to its small size, rapidly out of is chemically damaged dying cells leading to a rise in serum levels. Liver FABP is a sensitive marker for cell damage of liver cells in vitro and in vivo. Is chemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. Next to this L FABP is a marker for rapid hepatocyte lysis in vitro (as for example in toxicology assays) and for detection of liver damage during and after transplantation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 422 protein; Cardiac Fatty Acid Binding Protein; FABP 3; Fatty acid binding protein 11 (FABP11); Fatty acid binding protein 3 heart; Fatty acid binding protein heart; fatty acid binding protein heart 1; fatty acid binding protein heart 4; Fatty acid-binding protein 3; Fatty acid-binding protein, heart; H-FABP; heart FABP; heart fatty acid binding protein; Heart type fatty acid binding protein; Heart-type fatty acid-binding protein; M FABP; Mammary derived growth inhibitor; Mammary-derived growth inhibitor; MDGI; muscle and heart (mammary derived growth inhibitor); Muscle fatty acid binding protein; Muscle O-FABP; Mylein protein P2 homolog / adopocyte
Gene Aliases: Fabp3; Fabph-1; Fabph-4; Fabph1; Fabph4; H-FABP; Mdgi
UniProt ID: (Mouse) P11404, (Rat) P07483
Entrez Gene ID: (Mouse) 14077, (Rat) 79131
transport
long-chain fatty acid transport
cholesterol homeostasis
long-chain fatty acid import
regulation of fatty acid oxidation
phospholipid homeostasis
positive regulation of phospholipid biosynthetic process
regulation of phosphatidylcholine biosynthetic process
fatty acid metabolic process
fatty acid beta-oxidation
response to insulin
response to drug
response to fatty acid
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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