Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: ETVDLVLKLKN KLLQADREHL PVKPDTMEKL RTHIDAIILA LPEDLQGILL
Highest antigen sequence identity to the following orthologs - mouse 92%, rat 96%.
Guanine nucleotide exchange factor (GEF) for RAB14. Component of an endocytic recycling pathway that is required for the control of ADAM10 transport, shedding of N-cadherin/CDH2 by ADAM9 or ADAM10 and regulation of cell-cell junctions. Required for RAB14 recruitment to recycling endosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DENN domain-containing protein 6A; DENN/MADD domain containing 6A; family with sequence similarity 116, member A; Protein DENND6A; protein FAM116A
Gene Aliases: AFI1A; DENND6A; FAM116A
UniProt ID: (Human) Q8IWF6
Entrez Gene ID: (Human) 201627
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