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Product Details
68074-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2C10D7
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: ESWRSEVTFS TPALYIYTSG TTGATLALRT KFSASQFWDD CRKYNVTVIQ YIGELLRYLC NSPQKPNDRD HKVRLALGNG LRGDVWRQFV KRFGDICIYE FYAATEGNIG FMNYARKVGA VGRVNYLQKK IITYDLIKYD VEKDEPVRDE NGYCVRVPKG EVGLLVCKIT QLTPFNGYAG AKAQTEKKKL RDVFKKGDLY FNSGDLLMVD HENFIYFHDR VGDTFRWKGE NVATTEVADT VGLVDFVQEV NVYGVHVPDH EGRIGMASIK MKENHEFDGK KLFQHIADYL PSYARPRFLR IQDTIEITGT FKHRKMTLVE EGFNPAVIKD ALYFLDDTAK MYVPMTEDIY NAISAKTLKL
Target Information
The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Arachidonate--CoA ligase; FATP-2; Fatty acid transport protein 2; Fatty-acid-coenzyme A ligase, very long-chain 1; Long-chain fatty acid transport protein 2; Long-chain-fatty-acid--CoA ligase; Phytanate--CoA ligase; solute carrier family 27 (fatty acid transporter), member 2; solute carrier family 27 (fatty acid transporter), member 32; Solute carrier family 27 member 2; THCA-CoA ligase; ve; Very long-chain acyl-CoA synthetase; very long-chain fatty-acid-coenzyme A ligase 1; Very long-chain-fatty-acid-CoA ligase; very-long-chain acyl-CoA synthetase; VLACS; VLCS
Gene Aliases: ACSVL1; FACVL1; FATP2; hFACVL1; HsT17226; SLC27A2; VLACS; VLCS
UniProt ID: (Human) O14975, (Rat) P97524
Entrez Gene ID: (Human) 11001, (Rat) 65192
long-chain fatty acid-CoA ligase activity
receptor binding
ATP binding
fatty acid transporter activity
enzyme binding
very long-chain fatty acid-CoA ligase activity
phytanate-CoA ligase activity
pristanate-CoA ligase activity
decanoate--CoA ligase activity
protein binding
transporter
secondary carrier transporter
fatty acid alpha-oxidation
long-chain fatty acid metabolic process
fatty acid beta-oxidation
bile acid biosynthetic process
fatty acid transport
very long-chain fatty acid catabolic process
long-chain fatty acid import
methyl-branched fatty acid metabolic process
very long-chain fatty acid metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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