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Product Details
10696-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FBXO7 Fusion Protein Ag1035 (220-522 aa encoded by BC008361)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: KALSMPEKW KLSGVYKLQY MHPLCEGSSA TLTCVPLGNL IVVNATLKIN NEIRSVKRLQ LLPESFICKE KLGENVANIY KDLQKLSRLF KDQLVYPLLA FTRQALNLPD VFGLVVLPLE LKLRIFRLLD VRSVLSLSAV CRDLFTASND PLLWRFLYLR DFRDNTVRVQ DTDWKELYRK RHIQRKESPK GRFVMLLPSS THTIPFYPNP LHPRPFPSSR LPPGIIGGEY DQRPTLPYVG DPISSLIPGP GETPSQFPPL RPRFDPVGPL PGPNPILPGR GGPNDRFPFR PSRGRPTDGR LSFM (220-522 aa encoded by B C008361)
Target Information
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DKFZp686B08113; F-box only protein 7
Gene Aliases: 2410015K21Rik; A230052G17Rik; AI117679; AW260462; C85118; FBX; FBX07; FBX7; FBXO7; PARK15; PKPS
UniProt ID: (Human) Q9Y3I1, (Mouse) Q3U7U3
Entrez Gene ID: (Human) 25793, (Mouse) 69754
mitophagy
protein targeting to mitochondrion
protein ubiquitination
regulation of protein stability
negative regulation of lymphocyte differentiation
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of G1/S transition of mitotic cell cycle
ubiquitin-dependent protein catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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