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Product Details
PA5-61678
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human FECH. Recombinant protein control fragment (Product #RP-98224).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2641587
Product Specific Information
Immunogen sequence: THHLLIQCFA DHILKELDHF PLEKRSEVVI LFSAHSLPMS VVNRGDPYPQ EVSATVQKVM ERLEYCNPYR LVWQSKVGPM PWLGPQTDES IKGL
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 89%.
Target Information
The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ferrochelatase, mitochondrial; Heme synthase; heme synthetase; Protoheme ferro-lyase; protoporphyria
Gene Aliases: EPP; FCE; FECH
UniProt ID: (Human) P22830
Entrez Gene ID: (Human) 2235
generation of precursor metabolites and energy
heme biosynthetic process
response to light stimulus
response to lead ion
response to insecticide
response to drug
response to ethanol
protoporphyrinogen IX metabolic process
response to arsenic-containing substance
response to methylmercury
response to platinum ion
cellular response to dexamethasone stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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