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FGF5 Antibody (BS-1257R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded rat brain; Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (normal goat serum) at 37°C for 20min; Antibody incubation with FGF5 Polyclonal Antibody (bs-1257R) at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining.
Product Details
BS-1257R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human FGF5, amino acids 151-268.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FGF; FGF-5; Fibroblast growth factor; Fibroblast growth factor 5; fibroblast growth factor FGF-5; HBGF-5; Heparin-binding growth factor 5; Smag-82
Gene Aliases: angora; Fgf-5; FGF5; go; HBGF-5; Smag-82; TCMGLY
UniProt ID: (Human) P12034, (Mouse) P15656, (Rat) P48807
Entrez Gene ID: (Human) 2250, (Mouse) 14176, (Rat) 60662
protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
fibroblast growth factor receptor binding
growth factor activity
1-phosphatidylinositol-3-kinase activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
receptor binding
nerve growth factor receptor binding
growth factor
intercellular signal molecule
MAPK cascade
cell-cell signaling
nervous system development
cell proliferation
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
glial cell differentiation
regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
signal transduction involved in regulation of gene expression
phosphatidylinositol-3-phosphate biosynthetic process
positive regulation of GTPase activity
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
positive regulation of cell division
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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