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Product Details
CF807516
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OTI1C7
Immunogen
Human recombinant protein fragment corresponding to amino acids 89-205 of human FIGF produced in E.coli.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: c-fos induced growth factor (vascular endothelial growth factor D); c-Fos-induced growth factor; FIGF; Vascular endothelial growth factor D; VEGF-D; VEGF4
Gene Aliases: FIGF; VEGF-D; VEGFD
UniProt ID: (Human) O43915
Entrez Gene ID: (Human) 2277
angiogenesis
response to hypoxia
platelet degranulation
cell proliferation
positive regulation of cell proliferation
regulation of vascular endothelial growth factor receptor signaling pathway
positive regulation of interleukin-6 production
vascular endothelial growth factor receptor signaling pathway
positive chemotaxis
induction of positive chemotaxis
positive regulation of cell division
positive regulation of mast cell chemotaxis
response to interleukin-1
dopaminergic neuron differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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