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Proteintech
FOX2/RBM9 Monoclonal Antibody (2D7G5), CoraLite® Plus 488
Product Details
CL48866976100UL
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2D7G5
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Wet ice
Target Information
This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Fox-1 homolog B; Fox-1 homolog Fxh; fox-1 homologue; Fyn-binding molecule 2; Hexaribonucleotide-binding protein 2; Repressor of tamoxifen transcriptional activity; RNA binding protein fox-1 homolog 2; RNA binding protein, fox-1 homolog (C. elegans) 2; RNA-binding motif protein 9; RNA-binding protein 9
Gene Aliases: dJ106I20.3; Fbm2; Fox-2; FOX2; Fxh; HNRBP2; HRNBP2; RBFOX2; RBM9; RTA
UniProt ID: (Human) O43251, (Mouse) Q8BP71
Entrez Gene ID: (Human) 23543, (Mouse) 93686
regulation of alternative mRNA splicing, via spliceosome
mRNA processing
nervous system development
RNA splicing
fibroblast growth factor receptor signaling pathway
regulation of definitive erythrocyte differentiation
RNA metabolic process
radial glia guided migration of Purkinje cell
intracellular estrogen receptor signaling pathway
regulation of cell proliferation
negative regulation of transcription, DNA-templated
dendrite morphogenesis
neuromuscular process controlling balance
regulation of RNA splicing
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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