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Product Details
PA5-120007
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide within mouse FPR2 aa 163-025
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol, 0.2% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2913579
Product Specific Information
Positive Control: Hela, Jurkat, PC-3M, HL-60, mouse lung tissue, human lung tissue, mouse testis tissue, human spleen tissue, mouse spleen tissue
Subcellular Location: Cell membrane
Target Information
Formyl peptide receptor 2 (FPR2) is a low affinity receptor for N-formyl-methionyl peptides. Binding of FMLP to FPR2 causes activation of neutrophils. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FMLP-R-I; FMLP-related receptor I; fMLPR1; Formyl peptide receptor-like 1; FPR-like 1; Fpr-rs1; Fprl-1; HM63; Lipoxin A4 receptor; lipoxin A4 receptor (formyl peptide receptor related); Lipoxin receptor; LXA4 receptor; N-formyl peptide receptor 2; RFP
Gene Aliases: ALXR; FMLP-R-II; FMLPX; FPR2; FPR2A; FPRH1; FPRH2; FPRL1; HM63; LXA4R
UniProt ID: (Human) P25090
Entrez Gene ID: (Human) 2358
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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