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FIGURE: 1 / 2
Formyl peptide receptor 2 (FPR2) is a low affinity receptor for N-formyl-methionyl peptides. Binding of FMLP to FPR2 causes activation of neutrophils. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FMLP-R-I; FMLP-related receptor I; fMLPR1; Formyl peptide receptor 2; formyl peptide receptor, related sequence 2; formyl peptide receptor, related sequence 2-like; Formyl peptide receptor-like 1; Formylpeptide receptor-related sequence 2; FPR-like 1; Fpr-rs1; Fprl-1; HM63; Lipoxin A4 receptor; lipoxin A4 receptor (formyl peptide receptor related); Lipoxin A4 receptor-like protein; Lipoxin receptor; LXA4 receptor; N-formyl peptide receptor 2; N-formylpeptide receptor-like 2; RFP
Gene Aliases: ALXR; E330010I07Rik; FMLP-R-II; FMLPX; Fpr-rs2; FPR2; FPR2A; FPRH1; FPRH2; FPRL1; HM63; LXA4R
UniProt ID: (Human) P25090, (Mouse) O88536
Entrez Gene ID: (Human) 2358, (Mouse) 14289, (Rat) 690158
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