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Product Details
16197-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FRK Fusion Protein Ag10372 (235-505 aa encoded by BC012916)
Conjugate
Form
Liquid
Concentration
0.18 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: QLLKRLGSG QFGEVWEGLW NNTTPVAVKT LKPGSMDPND FLREAQIMKN LRHPKLIQLY AVCTLEDPIY IITELMRHGS LQEYLQNDTG SKIHLTQQVD MAAQVASGMA YLESRNYIHR DLAARNVLVG EHNIYKVADF GLARVFKVDN EDIYESRHEI KLPVKWTAPE AIRSNKFSIK SDVWSFGILL YEIITYGKMP YSGMTGAQVI QMLAQNYRLP QPSNCPQQFY NIMLECWNAE PKERPTFETL RWKLEDYFET DSSYSDANNF IR (235-505 aa encoded by BC012916)
Target Information
FRK (PTK5) is a nuclear protein and may function during G1 and S phase of the cell cycle, suppressing growth. The human FRK gene maps to chromosome 6q21-q22.3 and encodes a 505 amino acid protein. The protein belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B-cell src-homology tyrosine kinase; Beta-cell Src-homology tyrosine kinase; BSK; EC 2.7.1.112; EC 2.7.10.2; FYN-related kinase; fyn-related Src family tyrosine kinase; GASK; Gastrointestinal-associated kinase; Gastrointestinal-associated tyrosine kinase; GTK; Intestine tyrosine kinase; Nuclear tyrosine protein kinase RAK; Protein-tyrosine kinase 5; PTK5 protein tyrosine kinase 5; src related tyrosine kinase; Tyrosine-protein kinase FRK
Gene Aliases: BSK; BSK/IYK; C85044; FRK; Gask; GTK; Iyk; PTK5; RAK
UniProt ID: (Human) P42685, (Mouse) Q922K9, (Rat) Q62662
Entrez Gene ID: (Human) 2444, (Mouse) 14302, (Rat) 79209
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
phosphorylation
cell migration
peptidyl-tyrosine phosphorylation
actin cytoskeleton organization
cell differentiation
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
innate immune response
negative regulation of transcription from RNA polymerase II promoter
negative regulation of cell proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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