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FTCD Antibody (PA5-115255) in IHC (P)
Immunohistochemistry analysis of FTCD in mouse kidney tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115255) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Product Details
PA5-115255
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human FTCD(Accession O95954), corresponding to amino acid residues N186-T236.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2899891
Product Specific Information
Antibody detects endogenous levels of total FTCD.
Target Information
Golgi Protein, 58K is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 58 kDa microtubule-binding protein; Formimidoyltransferase-cyclodeaminase; formiminotransferase cyclodeaminase; Formiminotransferase-cyclodeaminase; FTCD; glutamate formiminotransferase; LCHC1
Gene Aliases: FTCD; LCHC1
UniProt ID: (Human) O95954, (Mouse) Q91XD4, (Rat) O88618
Entrez Gene ID: (Human) 10841, (Mouse) 14317, (Rat) 89833
histidine metabolic process
histidine catabolic process
cytoskeleton organization
metabolic process
cellular metabolic process
histidine catabolic process to glutamate and formamide
histidine catabolic process to glutamate and formate
tetrahydrofolate interconversion
folic acid-containing compound metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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