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Product Details
PA5-47569
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant human FUT5 Arg35-Thr374
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2609218
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
FUT3 comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This protein is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3; 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT5; 4-fucosyltransferase; 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase; 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5; alpha (1,3) fucosyltransferase; alpha-(1,3/1,4)-fucosyltransferase; Alpha-3-fucosyltransferase FUT3; Blood group Lewis alpha-4-fucosyltransferase; Fuc-TV; Fucosyltransferase 3; fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group); Fucosyltransferase 5; fucosyltransferase 5 (alpha (1,3) fucosyltransferase); Fucosyltransferase III; Fucosyltransferase V; FucT-III; fucT-V; Galactoside 3-L-fucosyltransferase; Lewis FT; Lewis Y
Gene Aliases: CD174; FT3B; FUC-TV; FucT-III; FUT3; FUT5; LE; Les
UniProt ID: (Human) P21217, (Human) Q11128
Entrez Gene ID: (Human) 2525, (Human) 2527
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