Proteintech

FUT4 Polyclonal Antibody

FUT4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 13

FUT4 Antibody (19497-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using 19497-1-AP ( FUT4 Antibody) at dilution of 1:400 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

FUT4 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

19497-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 16 publications 16 publications

Immunohistochemistry (IHC)

View 6 publications 6 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

View 10 publications 10 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

19497-1-AP antibody detects the native band around 59 kDa and glycosylated isoform proteins around 95-140 kDa in SDS-PAGE.

Target Information

FUT4 (Fucosyltransferase 4) is a Protein Coding gene. Diseases associated with FUT4 include Colon Adenocarcinoma and Liver Lymphoma. Among its related pathways are Glycosphingolipid biosynthesis - lacto and neolacto series and Mannose type O-glycan biosynthesis. Gene Ontology (GO) annotations related to this gene include fucosyltransferase activity and alpha-(1->3)-fucosyltransferase activity. The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Establishment of a Spermatogonial Stem Cell Line with Potential of Meiosis in a Hermaphroditic Fish, Epinephelus coioides.

Cells

Zhong C,Tao Y,Liu M,Wu X,Yang Y,Wang T,Meng Z,Xu H,Liu X

Wed Sep 14 00:00:00 EDT 2022

Sesquiterpene Lactones Attenuate Paclitaxel Resistance Via Inhibiting MALAT1/STAT3/ FUT4 Axis and P-Glycoprotein Transporters in Lung Cancer Cells.

Frontiers in pharmacology

Ding Y,Zhen Z,Nisar MA,Ali F,Din RU,Khan M,Mughal TA,Alam G,Liu L,Saleem MZ

Wed Mar 16 00:00:00 EDT 2022

Role of fucosyltransferase IV in the migration and invasion of human melanoma cells.

IUBMB life

Shan X,Dong W,Zhang L,Cai X,Zhao Y,Chen Q,Yan Q,Liu J

Fri May 01 00:00:00 EDT 2020

Role of fucosyltransferase IV in the migration and invasion of human melanoma cells.

IUBMB life

Shan X,Dong W,Zhang L,Cai X,Zhao Y,Chen Q,Yan Q,Liu J

Fri May 01 00:00:00 EDT 2020

Role of fucosyltransferase IV in the migration and invasion of human melanoma cells.

IUBMB life

Shan X,Dong W,Zhang L,Cai X,Zhao Y,Chen Q,Yan Q,Liu J

Fri May 01 00:00:00 EDT 2020

MyoD1 suppresses cell migration and invasion by inhibiting FUT4 transcription in human gastric cancer cells.

Cancer gene therapy

Wu F,Qin Y,Jiang Q,Zhang J,Li F,Li Q,Wang X,Gao Y,Miao J,Guo C,Yang Y,Ni L,Liu L,Zhang S,Huang C

Sun Nov 01 00:00:00 EDT 2020

Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro.

Stem cells international

Sun B,Luo X,Yang C,Liu P,Yang Y,Dong X,Yang Z,Xu J,Zhang Y,Li L

Thu May 13 00:00:00 EDT 2021

FUT4 is involved in PD-1-related immunosuppression and leads to worse survival in patients with operable lung adenocarcinoma.

Journal of cancer research and clinical oncology

Liu C,Li Z,Wang S,Fan Y,Zhang S,Yang X,Hou K,Tong J,Hu X,Shi X,Wang X,Liu Y,Che X,Qu X

Tue Jan 01 00:00:00 EST 2019

FUT4 is involved in PD-1-related immunosuppression and leads to worse survival in patients with operable lung adenocarcinoma.

Journal of cancer research and clinical oncology

Liu C,Li Z,Wang S,Fan Y,Zhang S,Yang X,Hou K,Tong J,Hu X,Shi X,Wang X,Liu Y,Che X,Qu X

Tue Jan 01 00:00:00 EST 2019

Neutrophils infiltration and its correlation with human papillomavirus status in the oral squamous cell carcinoma.

Cancer management and research

Li C,Zhao L,Wang Q,Ma S,Sun J,Ma C,Liu J,Jing X,Ai D,Nan Z,Qu X

Thu Oct 01 00:00:00 EDT 2020

Directing Induced Pluripotent Stem Cell Derived Neural Stem Cell Fate with a Three-Dimensional Biomimetic Hydrogel for Spinal Cord Injury Repair.

ACS applied materials & interfaces

Fan L,Liu C,Chen X,Zou Y,Zhou Z,Lin C,Tan G,Zhou L,Ning C,Wang Q

Wed May 30 00:00:00 EDT 2018

Directing Induced Pluripotent Stem Cell Derived Neural Stem Cell Fate with a Three-Dimensional Biomimetic Hydrogel for Spinal Cord Injury Repair.

ACS applied materials & interfaces

Fan L,Liu C,Chen X,Zou Y,Zhou Z,Lin C,Tan G,Zhou L,Ning C,Wang Q

Wed May 30 00:00:00 EDT 2018

Transcriptional Repression of p53 by PAX3 Contributes to Gliomagenesis and Differentiation of Glioma Stem Cells.

Frontiers in molecular neuroscience

Zhu H,Wang H,Huang Q,Liu Q,Guo Y,Lu J,Li X,Xue C,Han Q

Tue Sep 29 00:00:00 EDT 2020

Transcriptional Repression of p53 by PAX3 Contributes to Gliomagenesis and Differentiation of Glioma Stem Cells.

Frontiers in molecular neuroscience

Zhu H,Wang H,Huang Q,Liu Q,Guo Y,Lu J,Li X,Xue C,Han Q

Tue Sep 29 00:00:00 EDT 2020

AP1 mediates uPA/uPAR induced FUT4 expression and trophoblast invasion.

Journal of cellular biochemistry

Zheng Q,Yang Y,Cui X,Zhang D,Liu S,Yan Q

Wed Aug 01 00:00:00 EDT 2018

AP1 mediates uPA/uPAR induced FUT4 expression and trophoblast invasion.

Journal of cellular biochemistry

Zheng Q,Yang Y,Cui X,Zhang D,Liu S,Yan Q

Wed Aug 01 00:00:00 EDT 2018

AP1 mediates uPA/uPAR induced FUT4 expression and trophoblast invasion.

Journal of cellular biochemistry

Zheng Q,Yang Y,Cui X,Zhang D,Liu S,Yan Q

Wed Aug 01 00:00:00 EDT 2018

AP1 mediates uPA/uPAR induced FUT4 expression and trophoblast invasion.

Journal of cellular biochemistry

Zheng Q,Yang Y,Cui X,Zhang D,Liu S,Yan Q

Wed Aug 01 00:00:00 EDT 2018

MicroRNA-200c impairs uterine receptivity formation by targeting FUT4 and α1,3-fucosylation.

Cell death and differentiation

Zheng Q,Zhang D,Yang YU,Cui X,Sun J,Liang C,Qin H,Yang X,Liu S,Yan Q

Fri Dec 01 00:00:00 EST 2017

MicroRNA-200c impairs uterine receptivity formation by targeting FUT4 and α1,3-fucosylation.

Cell death and differentiation

Zheng Q,Zhang D,Yang YU,Cui X,Sun J,Liang C,Qin H,Yang X,Liu S,Yan Q

Fri Dec 01 00:00:00 EST 2017

MicroRNA-200c impairs uterine receptivity formation by targeting FUT4 and α1,3-fucosylation.

Cell death and differentiation

Zheng Q,Zhang D,Yang YU,Cui X,Sun J,Liang C,Qin H,Yang X,Liu S,Yan Q

Fri Dec 01 00:00:00 EST 2017

MicroRNA-200c impairs uterine receptivity formation by targeting FUT4 and α1,3-fucosylation.

Cell death and differentiation

Zheng Q,Zhang D,Yang YU,Cui X,Sun J,Liang C,Qin H,Yang X,Liu S,Yan Q

Fri Dec 01 00:00:00 EST 2017

miR-200b inhibits proliferation and metastasis of breast cancer by targeting fucosyltransferase IV and α1,3-fucosylated glycans.

Oncogenesis

Zheng Q,Cui X,Zhang D,Yang Y,Yan X,Liu M,Niang B,Aziz F,Liu S,Yan Q,Liu J

Mon Jul 10 00:00:00 EDT 2017

miR-200b inhibits proliferation and metastasis of breast cancer by targeting fucosyltransferase IV and α1,3-fucosylated glycans.

Oncogenesis

Zheng Q,Cui X,Zhang D,Yang Y,Yan X,Liu M,Niang B,Aziz F,Liu S,Yan Q,Liu J

Mon Jul 10 00:00:00 EDT 2017

miR-200b inhibits proliferation and metastasis of breast cancer by targeting fucosyltransferase IV and α1,3-fucosylated glycans.

Oncogenesis

Zheng Q,Cui X,Zhang D,Yang Y,Yan X,Liu M,Niang B,Aziz F,Liu S,Yan Q,Liu J

Mon Jul 10 00:00:00 EDT 2017

miR-200b inhibits proliferation and metastasis of breast cancer by targeting fucosyltransferase IV and α1,3-fucosylated glycans.

Oncogenesis

Zheng Q,Cui X,Zhang D,Yang Y,Yan X,Liu M,Niang B,Aziz F,Liu S,Yan Q,Liu J

Mon Jul 10 00:00:00 EDT 2017

Multivoxel magnetic resonance spectroscopy identifies enriched foci of cancer stem-like cells in high-grade gliomas.

OncoTargets and therapy

He T,Qiu T,Wang X,Gui H,Wang X,Hu Q,Xia H,Qi G,Wu J,Ma H

Thu Oct 01 00:00:00 EDT 2020

Multivoxel magnetic resonance spectroscopy identifies enriched foci of cancer stem-like cells in high-grade gliomas.

OncoTargets and therapy

He T,Qiu T,Wang X,Gui H,Wang X,Hu Q,Xia H,Qi G,Wu J,Ma H

Thu Oct 01 00:00:00 EDT 2020

Multivoxel magnetic resonance spectroscopy identifies enriched foci of cancer stem-like cells in high-grade gliomas.

OncoTargets and therapy

He T,Qiu T,Wang X,Gui H,Wang X,Hu Q,Xia H,Qi G,Wu J,Ma H

Thu Oct 01 00:00:00 EDT 2020

Multivoxel magnetic resonance spectroscopy identifies enriched foci of cancer stem-like cells in high-grade gliomas.

OncoTargets and therapy

He T,Qiu T,Wang X,Gui H,Wang X,Hu Q,Xia H,Qi G,Wu J,Ma H

Thu Oct 01 00:00:00 EDT 2020

Fucosyltransferase-4 and Oligosaccharide Lewis Y Antigen as potentially Correlative Biomarkers of Helicobacter pylori CagA Associated Gastric Cancer.

Pathology oncology research : POR

Aziz F,Gao W,Yan Q

Sun Jan 01 00:00:00 EST 2017

Fucosyltransferase-4 and Oligosaccharide Lewis Y Antigen as potentially Correlative Biomarkers of Helicobacter pylori CagA Associated Gastric Cancer.

Pathology oncology research : POR

Aziz F,Gao W,Yan Q

Sun Jan 01 00:00:00 EST 2017

Novel function of pregnancy-associated plasma protein A: promotes endometrium receptivity by up-regulating N-fucosylation.

Scientific reports

Yu M,Wang J,Liu S,Wang X,Yan Q

Thu Jul 13 00:00:00 EDT 2017

Novel function of pregnancy-associated plasma protein A: promotes endometrium receptivity by up-regulating N-fucosylation.

Scientific reports

Yu M,Wang J,Liu S,Wang X,Yan Q

Thu Jul 13 00:00:00 EDT 2017

Novel function of pregnancy-associated plasma protein A: promotes endometrium receptivity by up-regulating N-fucosylation.

Scientific reports

Yu M,Wang J,Liu S,Wang X,Yan Q

Thu Jul 13 00:00:00 EDT 2017

Novel function of pregnancy-associated plasma protein A: promotes endometrium receptivity by up-regulating N-fucosylation.

Scientific reports

Yu M,Wang J,Liu S,Wang X,Yan Q

Thu Jul 13 00:00:00 EDT 2017

Ginsenoside Rg3 induces FUT4-mediated apoptosis in H. pylori CagA-treated gastric cancer cells by regulating SP1 and HSF1 expressions.

Toxicology in vitro : an international journal published in association with BIBRA

Aziz F,Wang X,Liu J,Yan Q

Tue Mar 01 00:00:00 EST 2016

Ginsenoside Rg3 induces FUT4-mediated apoptosis in H. pylori CagA-treated gastric cancer cells by regulating SP1 and HSF1 expressions.

Toxicology in vitro : an international journal published in association with BIBRA

Aziz F,Wang X,Liu J,Yan Q

Tue Mar 01 00:00:00 EST 2016

Ginsenoside Rg3 induces FUT4-mediated apoptosis in H. pylori CagA-treated gastric cancer cells by regulating SP1 and HSF1 expressions.

Toxicology in vitro : an international journal published in association with BIBRA

Aziz F,Wang X,Liu J,Yan Q

Tue Mar 01 00:00:00 EST 2016

Ginsenoside Rg3 induces FUT4-mediated apoptosis in H. pylori CagA-treated gastric cancer cells by regulating SP1 and HSF1 expressions.

Toxicology in vitro : an international journal published in association with BIBRA

Aziz F,Wang X,Liu J,Yan Q

Tue Mar 01 00:00:00 EST 2016

Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4.

Oncotarget

Tian L,Shen D,Li X,Shan X,Wang X,Yan Q,Liu J

Tue Jan 12 00:00:00 EST 2016

Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4.

Oncotarget

Tian L,Shen D,Li X,Shan X,Wang X,Yan Q,Liu J

Tue Jan 12 00:00:00 EST 2016

Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4.

Oncotarget

Tian L,Shen D,Li X,Shan X,Wang X,Yan Q,Liu J

Tue Jan 12 00:00:00 EST 2016

Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4.

Oncotarget

Tian L,Shen D,Li X,Shan X,Wang X,Yan Q,Liu J

Tue Jan 12 00:00:00 EST 2016

Ginsenoside Rg3-induced EGFR/MAPK pathway deactivation inhibits melanoma cell proliferation by decreasing FUT4/LeY expression.

International journal of oncology

Shan X,Aziz F,Tian LL,Wang XQ,Yan Q,Liu JW

Wed Apr 01 00:00:00 EDT 2015

Ginsenoside Rg3 suppresses FUT4 expression through inhibiting NF-κB/p65 signaling pathway to promote melanoma cell death.

International journal of oncology

Shan X,Tian LL,Zhang YM,Wang XQ,Yan Q,Liu JW

Sat Aug 01 00:00:00 EDT 2015

Ginsenoside Rg3 suppresses FUT4 expression through inhibiting NF-κB/p65 signaling pathway to promote melanoma cell death.

International journal of oncology

Shan X,Tian LL,Zhang YM,Wang XQ,Yan Q,Liu JW

Sat Aug 01 00:00:00 EDT 2015

Anti-LeY antibody enhances therapeutic efficacy of celecoxib against gastric cancer by downregulation of MAPKs/COX-2 signaling pathway: correlation with clinical study.

Journal of cancer research and clinical oncology

Aziz F,Yang X,Wang X,Yan Q

Wed Jul 01 00:00:00 EDT 2015

Anti-LeY antibody enhances therapeutic efficacy of celecoxib against gastric cancer by downregulation of MAPKs/COX-2 signaling pathway: correlation with clinical study.

Journal of cancer research and clinical oncology

Aziz F,Yang X,Wang X,Yan Q

Wed Jul 01 00:00:00 EDT 2015

Baicalin promotes embryo adhesion and implantation by upregulating fucosyltransferase IV (FUT4) via Wnt/beta-catenin signaling pathway.

FEBS letters

Zhang YM,Zhang YY,Bulbul A,Shan X,Wang XQ,Yan Q

Fri May 08 00:00:00 EDT 2015

Baicalin promotes embryo adhesion and implantation by upregulating fucosyltransferase IV (FUT4) via Wnt/beta-catenin signaling pathway.

FEBS letters

Zhang YM,Zhang YY,Bulbul A,Shan X,Wang XQ,Yan Q

Fri May 08 00:00:00 EDT 2015

Baicalin promotes embryo adhesion and implantation by upregulating fucosyltransferase IV (FUT4) via Wnt/beta-catenin signaling pathway.

FEBS letters

Zhang YM,Zhang YY,Bulbul A,Shan X,Wang XQ,Yan Q

Fri May 08 00:00:00 EDT 2015

Baicalin promotes embryo adhesion and implantation by upregulating fucosyltransferase IV (FUT4) via Wnt/beta-catenin signaling pathway.

FEBS letters

Zhang YM,Zhang YY,Bulbul A,Shan X,Wang XQ,Yan Q

Fri May 08 00:00:00 EDT 2015

Role of fucosyltransferase IV in epithelial-mesenchymal transition in breast cancer cells.

Cell death & disease

Yang X,Liu S,Yan Q

Thu Jul 25 00:00:00 EDT 2013

Role of fucosyltransferase IV in epithelial-mesenchymal transition in breast cancer cells.

Cell death & disease

Yang X,Liu S,Yan Q

Thu Jul 25 00:00:00 EDT 2013

Bioinformatics

Protein Aliases: 3-fucosyl-N-acetyl-lactosamine epitope; 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase; alpha (1,3) fucosyltransferase, myeloid specific; alpha (1,3) fucosyltransferase, myeloid-specific; alpha 1,3-fucosyltransferase; Alpha-(1,3)-fucosyltransferase 4; ELAM ligand fucosyltransferase; ELAM-1 ligand fucosyltransferase; Fuc-TIV; Fucosyltransferase 4; fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific); Fucosyltransferase IV; fucT-IV; Galactoside 3-L-fucosyltransferase; Lewis X; stage-specific embryonic antigen 1

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Gene Aliases: AI451562; CD15; ELFT; FAL; FCT3A; FUC-TIV; FucT-IV; FUT4; FUTIV; LeX; SSEA-1; Ssea1

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UniProt ID: (Human) P22083, (Mouse) Q11127

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Entrez Gene ID: (Human) 2526, (Mouse) 14345

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Function(s)

Process(es)

carbohydrate metabolic process protein glycosylation protein N-linked glycosylation fucosylation L-fucose catabolic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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FUT4 Polyclonal Antibody

FUT4 Antibody (19497-1-AP) in IHC (P)

Product Details

19497-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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