Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 1
FXN Antibody (PA5-97763) in WB
Western Blot analysis of FXN using a FXN Polyclonal antibody (Product # PA5-97763) at a concentration of 2 µg/mL. Lane 1: HepG2 whole cell lysate. Lane 2: Hela whole cell lysate. Lane 3: Mouse brain tissue. Lane 4: Jurkat whole cell lysate. A secondary Goat polyclonal antibody to rabbit IgG was applied at a 1:10,000 dilution. Observed band size: 23 kDa.
Product Details
PA5-97763
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Mouse Frataxin, mitochondrial protein (78-207AA)
Conjugate
Form
Liquid
Concentration
2.5 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_2812378
Target Information
FXN is a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Frataxin, mitochondrial; Friedreich ataxia; Friedreich ataxia protein; Fxn
Gene Aliases: CyaY; FA; FARR; FRDA; FXN; X25
UniProt ID: (Human) Q16595, (Mouse) O35943
Entrez Gene ID: (Human) 2395, (Mouse) 14297
oxidative phosphorylation
heme biosynthetic process
ion transport
cellular iron ion homeostasis
mitochondrion organization
adult walking behavior
positive regulation of cell proliferation
aerobic respiration
embryo development ending in birth or egg hatching
response to iron ion
regulation of ferrochelatase activity
protein autoprocessing
iron incorporation into metallo-sulfur cluster
proprioception
positive regulation of cell growth
negative regulation of multicellular organism growth
negative regulation of apoptotic process
positive regulation of catalytic activity
small molecule metabolic process
negative regulation of organ growth
positive regulation of lyase activity
cellular response to hydrogen peroxide
negative regulation of release of cytochrome c from mitochondria
positive regulation of succinate dehydrogenase activity
positive regulation of aconitate hydratase activity
transport
iron-sulfur cluster assembly
positive regulation of axon extension
positive regulation of transferase activity
positive regulation of oxidoreductase activity
iron ion homeostasis
oxidation-reduction process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support