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Factor B is a component of the alternative complement pathway. The protein is a single chain polypeptide with a molecular mass of 93 kDa. Factor B is cleaved by factor D into the Ba component (30 kDa) and the Bb (63 kDa). Bb together with C3b forms the alternative pathway C3 convertase C3bBb.
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Protein Aliases: alternative-complement pathway C3/C5 convertase; B-factor, properdin; C3 proaccelerator; C3 proactivator; C3/C5 convertase; complement component 2 (within H-2S); Complement factor B; DADB-122G4.5; Factor B; GBG; Glycine-rich beta glycoprotein; glycine-rich beta-glycoprotein; histocompatibility 2, complement component factor B; PBF2; properdin; Properdin factor B
Gene Aliases: AHUS4; AI195813; AI255840; ARMD14; B; BF; BFD; C2; CFAB; CFB; CFBD; Da1-24; FB; FBI12; GBG; H2-Bf; PBF2
UniProt ID: (Human) P00751
Entrez Gene ID: (Human) 629, (Mouse) 14962, (Rat) 294257
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