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Product Details
MA1-43038
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rat
/ IgG
Class
Monoclonal
Type
Antibody
Clone
9031
Immunogen
Mouse Factor VII.
Conjugate
Form
Liquid
Purification
Ion-exchange chromatography, Ammonium sulfate precipitation
Storage buffer
50% water with 50% glycerol
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2101609
Product Specific Information
MA1-43038 detects Factor VII in mouse samples.
MA1-43038 has successfully been used in Western blot and ELISA applications.
MA1-43038 was derived from mouse factor VII.
Target Information
Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in F7 production can cause coagulopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Coagulation factor VII; Factor 7; Factor7; Serum prothrombin conversion accelerator
Gene Aliases: AI132620; Cf7; F7; FVII
UniProt ID: (Mouse) P70375
Entrez Gene ID: (Mouse) 14068
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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