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Product Details
MA5-17633
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
AA-3
Immunogen
Human Factor VII (AA-3) purified from plasma.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2539023
Product Specific Information
MA5-17633 targets Factor VII/VIIa in ELISA and WB applications and shows reactivity with Human samples.
The MA5-17633 immunogen is human Factor VII (AA-3) purified from plasma.
Target Information
Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in F7 production can cause coagulopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Coagulation factor VII; coagulation factor VII (serum prothrombin conversion accelerator); eptacog alfa; Factor 7; Factor7; FVII coagulation protein; Proconvertin; Serum prothrombin conversion accelerator; SPCA
Gene Aliases: F7; SPCA
UniProt ID: (Human) P08709
Entrez Gene ID: (Human) 2155
positive regulation of leukocyte chemotaxis
signal peptide processing
ER to Golgi vesicle-mediated transport
blood coagulation
blood coagulation, extrinsic pathway
circadian rhythm
positive regulation of platelet-derived growth factor receptor signaling pathway
response to organic cyclic compound
protein processing
peptidyl-glutamic acid carboxylation
positive regulation of blood coagulation
positive regulation of cell migration
organ regeneration
response to vitamin K
response to estrogen
positive regulation of positive chemotaxis
positive regulation of protein kinase B signaling
response to growth hormone
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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