Product References
A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise.
Cell stem cell
Gadomski S,Fielding C,García-García A,Korn C,Kapeni C,Ashraf S,Villadiego J,Toro RD,Domingues O,Skepper JN,Michel T,Zimmer J,Sendtner R,Dillon S,Poole KES,Holdsworth G,Sendtner M,Toledo-Aral JJ,De Bari C,McCaskie AW,Robey PG,Méndez-Ferrer S
A-11096 was used in Immunohistochemistry to uncover a cholinergic neuro-osteocyte interface that regulates skeletogenesis and skeletal turnover through bone-anabolic effects.
Thu Apr 07 00:00:00 EDT 2022
The tumor suppressor adenomatous polyposis coli regulates T lymphocyte migration.
Science advances
Mastrogiovanni M,Vargas P,Rose T,Cuche C,Esposito E,Juzans M,Laude H,Schneider A,Bernard M,Goyard S,Renaudat C,Ungeheuer MN,Delon J,Alcover A,Di Bartolo V
A-11096 was used in Immunocytochemistry-immunofluorescence to find that APC affects T cell motility by modulating integrin-dependent adhesion and cytoskeleton reorganization.
Fri Apr 15 00:00:00 EDT 2022
The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake.
Immunity
de Mingo Pulido Á,Hänggi K,Celias DP,Gardner A,Li J,Batista-Bittencourt B,Mohamed E,Trillo-Tinoco J,Osunmakinde O,Peña R,Onimus A,Kaisho T,Kaufmann J,McEachern K,Soliman H,Luca VC,Rodriguez PC,Yu X,Ruffell B
A-11096 was used in Immunocytochemistry-immunofluorescence to report that increased CXCL9 expression by splenic cDC1s upon TIM-3 blockade required type I interferons and extracellular DNA.
Tue Jun 08 00:00:00 EDT 2021
Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury.
Nature neuroscience
Ydens E,Amann L,Asselbergh B,Scott CL,Martens L,Sichien D,Mossad O,Blank T,De Prijck S,Low D,Masuda T,Saeys Y,Timmerman V,Stumm R,Ginhoux F,Prinz M,Janssens S,Guilliams M
A-11096 was used in Immunohistochemistry to perform ontogenic, transcriptomic and spatial characterization of sciatic nerve macrophages (snMacs).
Fri May 01 00:00:00 EDT 2020
Id1 and Id3 Maintain Steady-State Hematopoiesis by Promoting Sinusoidal Endothelial Cell Survival and Regeneration.
Cell reports
Gadomski S,Singh SK,Singh S,Sarkar T,Klarmann KD,Berenschot M,Seaman S,Jakubison B,Gudmundsson KO,Lockett S,Keller JR
A-11096 was used in Immunohistochemistry to investigate the effects of loss of ld genes on adult endothelial cell.
Tue Apr 28 00:00:00 EDT 2020
Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell-mediated tumor regression.
The Journal of experimental medicine
Etzerodt A,Tsalkitzi K,Maniecki M,Damsky W,Delfini M,Baudoin E,Moulin M,Bosenberg M,Graversen JH,Auphan-Anezin N,Moestrup SK,Lawrence T
A-11096 was used in Immunohistochemistry to study the immune-suppressive function for CD163+ TAM in melanoma that is independent of the PD-1/PD-L1 axis.
Mon Oct 07 00:00:00 EDT 2019
Vascular adhesion protein-1 is actively involved in the development of inflammatory lesions in rat models of multiple sclerosis.
Journal of neuroinflammation
Elo P,Tadayon S,Liljenbäck H,Teuho J,Käkelä M,Koskensalo K,Saunavaara V,Virta J,Veres TZ,Kiviniemi A,Saraste A,Marjamäki P,Airas L,Jalkanen S,Roivainen A
A-11096 was used in Immunohistochemistry-immunofluorescence to investigate the expression of vascular adhesion protein-1 within the central nervous system vasculature in two focal rat models of experimental autoimmune encephalomyelitis mimicking multiple sclerosis.
Tue May 01 00:00:00 EDT 2018
Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature.
Cancer cell
Seaman S,Zhu Z,Saha S,Zhang XM,Yang MY,Hilton MB,Morris K,Szot C,Morris H,Swing DA,Tessarollo L,Smith SW,Degrado S,Borkin D,Jain N,Scheiermann J,Feng Y,Wang Y,Li J,Welsch D,DeCrescenzo G,Chaudhary A,Zudaire E,Klarmann KD,Keller JR,Dimitrov DS,St Croix B
A-11096 was used in an ELISA assay to demonstrate that the cell surface protein CD276/B7-H3 is broadly over-expressed by multiple tumour types on both cancer cells and tumour-infiltrating blood vessels, making it a potentially ideal dual-compartment therapeutic target.
Mon Apr 10 00:00:00 EDT 2017
Myeloperoxidase targets oxidative host attacks to Salmonella and prevents collateral tissue damage.
Nature microbiology
Schürmann N,Forrer P,Casse O,Li J,Felmy B,Burgener AV,Ehrenfeuchter N,Hardt WD,Recher M,Hess C,Tschan-Plessl A,Khanna N,Bumann D
A-11096 was used in ELISA, Immunohistochemistry to show that myeloperoxidase has a major function in mitigating collateral tissue damage during antimicrobial oxidative bursts, by converting diffusible long-lived H2O2 into highly reactive, microbicidal and locally confined HOCl at pathogen surfaces.
Mon Jan 23 00:00:00 EST 2017
Ghrelin activates hypophysiotropic corticotropin-releasing factor neurons independently of the arcuate nucleus.
Psychoneuroendocrinology
Cabral A,Portiansky E,Sánchez-Jaramillo E,Zigman JM,Perello M
A11096 was used in immunohistochemistry to elucidate the mechanism by which ghrelin activates paraventricular nucleus corticotropin-releasing factor neurons
Sun May 01 00:00:00 EDT 2016
Des-Acyl Ghrelin Directly Targets the Arcuate Nucleus in a Ghrelin-Receptor Independent Manner and Impairs the Orexigenic Effect of Ghrelin.
Journal of neuroendocrinology
Fernandez G,Cabral A,Cornejo MP,De Francesco PN,Garcia-Romero G,Reynaldo M,Perello M
A-11096 was used in immunohistochemistry to determine impairment of the orexigenic effect of ghrelin and targeting the arcuate nucleus in a ghrelin-receptor independent manner by des-acyl ghrelin
Mon Feb 01 00:00:00 EST 2016
Parallel inputs from the mediodorsal thalamus to the prefrontal cortex in the rat.
The European journal of neuroscience
Alcaraz F,Marchand AR,Courtand G,Coutureau E,Wolff M
A-11096 was used in immunohistochemistry to investigate mediodorsal thalamus parallel inputs to the prefrontal cortex in the rat
Mon Aug 01 00:00:00 EDT 2016
A homeobox protein, NKX6.1, up-regulates interleukin-6 expression for cell growth in basal-like breast cancer cells.
Experimental cell research
Li W,Itou J,Tanaka S,Nishimura T,Sato F,Toi M
A-11096 was used in ELISA, Immunocytochemistry to conclude that NKX6.1 is a factor for IL-6-regulated growth and tumor formation in basal-like breast cancer.
Sun May 01 00:00:00 EDT 2016
Flexible Use of Predictive Cues beyond the Orbitofrontal Cortex: Role of the Submedius Thalamic Nucleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Alcaraz F,Marchand AR,Vidal E,Guillou A,Faugère A,Coutureau E,Wolff M
A-11096 was used in immunohistochemistry to study the role of the orbitofrontal cortex in learning guided behavior.
Wed Sep 23 00:00:00 EDT 2015
An optical labeling-based proliferation assay system reveals the paracrine effect of interleukin-6 in breast cancer.
Biochimica et biophysica acta
Itou J,Tanaka S,Sato F,Akiyama R,Kawakami Y,Toi M
A-11096 was used in Immunohistochemistry-immunofluorescence to indicate that in basal-like breast cancer cells, IL-6 exhibits a paracrine effect to positively regulate cell proliferation.
Thu Jan 01 00:00:00 EST 2015
Ghrelin's Orexigenic Effect Is Modulated via a Serotonin 2C Receptor Interaction.
ACS chemical neuroscience
Schellekens H,De Francesco PN,Kandil D,Theeuwes WF,McCarthy T,van Oeffelen WE,Perelló M,Giblin L,Dinan TG,Cryan JF
A-11096 was used in immunocytochemistry to investigate the relationship between the GHS-R1a receptor and the 5-HT2C receptor
Wed Jul 15 00:00:00 EDT 2015
DNA vaccines: MHC II-targeted vaccine protein produced by transfected muscle fibres induces a local inflammatory cell infiltrate in mice.
PloS one
Løvås TO,Bruusgaard JC,Øynebråten I,Gundersen K,Bogen B
A-11096 was used in Immunofluorescence in immunohistochemistry on frozen tissues to study the mechanisms behind the improved immunogenicity of targeted DNA vaccines over non-targeted naked DNA vaccines.
Tue Jun 16 00:00:00 EDT 2015
Analysis of brain nuclei accessible to ghrelin present in the cerebrospinal fluid.
Neuroscience
Cabral A,Fernandez G,Perello M
Published figure using Fluorescein/Oregon Green polyclonal antibody (Product # A-11096) in Immunofluorescence
Tue Dec 03 00:00:00 EST 2013
Characterization of pluripotent stem cells.
Nature protocols
Martí M,Mulero L,Pardo C,Morera C,Carrió M,Laricchia-Robbio L,Esteban CR,Izpisua Belmonte JC
A-11096 was used in Immunocytochemistry-immunofluorescence to provide a protocol describing immunodetection procedures which can be used to characterise mouse and human stem cell lines and detect hallmarks of pluripotency which is fast and reliable for the registration of stem cell lines.
Fri Feb 01 00:00:00 EST 2013
Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma.
The Journal of experimental medicine
Cook N,Frese KK,Bapiro TE,Jacobetz MA,Gopinathan A,Miller JL,Rao SS,Demuth T,Howat WJ,Jodrell DI,Tuveson DA
A-11096 was used in immunohistochemistry - paraffin section to examine the effects of a gamma secretase inhibitor on intratumoral Notch signaling in a mouse model of pancreatic ductal adenocarcinoma
Mon Mar 12 00:00:00 EDT 2012
Inflammatory spleen monocytes can upregulate CD11c expression without converting into dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Drutman SB,Kendall JC,Trombetta ES
A-11096 was used in immunohistochemistry - frozen section to study upregulation of CD11c expression without converting into dendritic cells by inflammatory spleen monocytes
Sun Apr 15 00:00:00 EDT 2012
Analysis of the paired TCR α- and β-chains of single human T cells.
PloS one
Kim SM,Bhonsle L,Besgen P,Nickel J,Backes A,Held K,Vollmer S,Dornmair K,Prinz JC
A-11096 was used in Immunohistochemistry-immunofluorescence to develop a protocol for the unbiased analysis of the complete sequences of both α- and Β-chains of the TCR from single T cells.
Tue Oct 09 00:00:00 EDT 2012
The stromal cell antigen CD248 (endosialin) is expressed on naive CD8+ human T cells and regulates proliferation.
Immunology
Hardie DL,Baldwin MJ,Naylor A,Haworth OJ,Hou TZ,Lax S,Curnow SJ,Willcox N,MacFadyen J,Isacke CM,Buckley CD
A-11096 was used in Immunohistochemistry-immunofluorescence to demonstrate opposing functions for CD248 on haematopoietic) versus stromal cells.
Fri Jul 01 00:00:00 EDT 2011
Association of T-zone reticular networks and conduits with ectopic lymphoid tissues in mice and humans.
The American journal of pathology
Link A,Hardie DL,Favre S,Britschgi MR,Adams DH,Sixt M,Cyster JG,Buckley CD,Luther SA
A-11096 was used in immunohistochemistry to characterize tertiary lymphoid tissues.
Fri Apr 01 00:00:00 EDT 2011
Colocalization of hyperpolarization-activated, cyclic nucleotide-gated channel subunits in rat retinal ganglion cells.
The Journal of comparative neurology
Stradleigh TW,Ogata G,Partida GJ,Oi H,Greenberg KP,Krempely KS,Ishida AT
Published figure using Fluorescein/Oregon Green polyclonal antibody (Product # A-11096) in Immunofluorescence
Thu Sep 01 00:00:00 EDT 2011
Multiple sclerosis: T-cell receptor expression in distinct brain regions.
Brain : a journal of neurology
Junker A,Ivanidze J,Malotka J,Eiglmeier I,Lassmann H,Wekerle H,Meinl E,Hohlfeld R,Dornmair K
A-11096 was used in Immunohistochemistry-immunofluorescence to compare the T-cell receptor repertoire in distinct lesions and normal-appearing white matter from post-mortem brains of four multiple sclerosis patients.
Thu Nov 01 00:00:00 EDT 2007
Kinesin I-dependent cortical exclusion restricts pole plasm to the oocyte posterior.
Nature cell biology
Cha BJ,Serbus LR,Koppetsch BS,Theurkauf WE
A-11096 was used in immunohistochemistry to study how oskar mRNA associates with the posterior pole
Thu Aug 01 00:00:00 EDT 2002