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Product Details
CL555-66486
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1E4A2
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
555/570 nm
Form
Liquid
Purification
Protein G
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20° C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: PDDSGTFYDQ AVVSNDMEEH LEEPVAEPEP DPEPEPEQEP VSEIQEEKPE PVLEETAPED AQKSSSPAPA DIAQTVQEDL RTFSWASVTS KNLPPSGAVP VTGIPPHVVK VPASQPRPES KPESQIPPQR PQRDQRVREQ RINIPPQRGP RPIREAGEQG DIEPRRMVRH PDSHQLFIGN LPHEVDKSEL KDFFQSYGNV VELRINSGGK LPNFGFVVFD DSEPVQKVLS NRPIMFRGEV RLNVEEKKTR AAREGDRRDN RLRGPGGPRG GLGGGMRGPP RGGMVQKPGF GVGRGLAPRQ
Target Information
This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-dependent DNA helicase VIII; DNA helicase VIII; G3BP-1; GAP binding protein; GAP SH3 binding protein; GAP SH3 domain-binding protein 1; GTPase activating protein (SH3 domain) binding protein 1; hDH VIII; HDH-VIII; MGC111040; Ras GTPase-activating protein-binding protein 1; Ras-GTPase-activating protein SH3-domain binding protein 1; Ras-GTPase-activating protein SH3-domain-binding protein; RasGAP-associated endoribonuclease G3BP
Gene Aliases: AI849976; B430204O07; C87777; G3BP; G3BP1; HDH-VIII; mKIAA4115; RGD1310666
UniProt ID: (Human) Q13283, (Mouse) P97855
Entrez Gene ID: (Pig) 100513766, (Human) 10146, (Rat) 171092, (Mouse) 27041
DNA binding
mRNA binding
ATP-dependent DNA helicase activity
ATP-dependent RNA helicase activity
endonuclease activity
protein binding
ATP binding
poly(A) RNA binding
nucleotide binding
nucleic acid binding
RNA binding
helicase activity
nuclease activity
hydrolase activity
RNA metabolism protein
nucleic acid metabolism protein
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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