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Alomone Labs, LTD
GABA Transporter 1 (GAT-1) (extracellular) Polyclonal Antibody
FIGURE: 1 / 2
GABA Transporter 1 (GAT-1) (extracellular) Antibody (AGT-001-200UL) in IHC
Expression of GABATR in rat cerebellum - Immunohistochemical staining of rat cerebellum using Anti-GABA Transporter 1 (GAT-1) (extracellular) Antibody (#AGT-001), (1:200). A. GAT-1 staining is shown in green. B. Neurons expressing gamma amino butyric acid (GABA) were labeled with mouse Anti-parvalbumin (red). C. Merge of the two images demonstrates partial colocalization (arrows). GAT-1 appears both in the ... View More
Product Details
AGT-001-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)ERNMHQMTDGLDK, corresponding to amino acids residues 194-206 of rat GAT-1, 2nd extracellular loop
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
GAT-1 (SLC6A1) The protein encoded by SLC6A1 is a gamma-aminobutyric acid (GABA) transporter that localizes to the plasma membrane. The encoded protein removes GABA from the synaptic cleft, restoring it to presynaptic terminals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GABA T-1; GABA T1; GABA transporter 1; GABA transporter protein; GABAT1; gamma-aminobutyric acid (GABA-A) transporter 1; GAT-1; Sodium- and chloride-dependent GABA transporter 1; solute carrier family 6 (neurotransmitter transporter), member 1; solute carrier family 6 (neurotransmitter transporter, GABA), member 1; Solute carrier family 6 member 1
Gene Aliases: A730043E01; GABATHG; GABATR; Gabt; GABT1; GAT-1; GAT1; MAE; SLC6A1; XT-1; Xtrp1
UniProt ID: (Human) P30531, (Rat) P23978, (Mouse) P31648
Entrez Gene ID: (Human) 6529, (Rat) 79212, (Mouse) 232333
transport
neurotransmitter transport
chemical synaptic transmission
learning
response to toxic substance
response to sucrose
response to lead ion
positive regulation of gamma-aminobutyric acid secretion
response to purine-containing compound
gamma-aminobutyric acid transport
negative regulation of synaptic transmission, GABAergic
response to estradiol
response to cocaine
protein homooligomerization
response to calcium ion
gamma-aminobutyric acid import
transmembrane transport
mitophagy in response to mitochondrial depolarization
response to organic substance
response to organonitrogen compound
response to organic cyclic compound
amino acid transmembrane transport
sodium ion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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