Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 1
GAP43 Antibody (MA5-47386) in ICC/IF
Immunocytochemistry analysis of GAP43 in mixed neuronal cultures stained. Samples were stained with GAP43 monoclonal antibody (Product # MA5-47386) in green. Costained with a rabbit antibody to microtubule associated protein 2 (MAP2, red) and DNA (blue). The GAP43 antibody stains the plasma membrane of neurons and is particularly concentrated in dendrites.
Product Details
MA5-47386
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1E3
Immunogen
C-terminal peptide of rat and mouse GAP43, which is KEDPEADQEHA, with an N-terminal Cys added to allow chemical coupling to KLH carrier protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 50% glycerol
Contains
5mM sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2942368
Target Information
GAP43 (Neuromodulin) is associated with nerve growth. GAP43 is expressed by developing and regenerating neurons, and to a lesser extent reactive glial cells. It is a major component of the motile "growth cones" that form the tips of elongating axons. GAP43 also plays a role in axonal and dendritic filopodia induction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Axonal membrane protein GAP-43; brain abundant, membrane attached signal protein 2; Calmodulin-binding protein P-57; growth accentuating protein 43; Growth-associated protein 43; MGC156666; nerve growth-related peptide GAP43; Neural phosphoprotein B-50; Neuromodulin; neuron growth-associated protein 43; neuron protein F1; pp46; Protein F1
Gene Aliases: B-50; Basp2; GAP-43; GAP43; PP46
UniProt ID: (Human) P17677, (Rat) P07936, (Mouse) P06837
Entrez Gene ID: (Human) 2596, (Rat) 29423, (Mouse) 14432
nervous system development
axon guidance
glial cell differentiation
axon choice point recognition
regulation of growth
tissue regeneration
cell fate commitment
regulation of filopodium assembly
axon development
multicellular organism development
cell differentiation
protein kinase C-activating G-protein coupled receptor signaling pathway
response to wounding
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support