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GATA4 Antibody (PA5-11438) in WB
Western blot analysis of GATA4 in 293 cell lysates. Samples were incubated with GATA4 polyclonal antibody (Product # PA5-11438). Lysates: 2 µg/lane. 293 cell lysates either nontransfected (Lane 1) or transiently transfected with the GATA4 gene (Lane 2).
Product Details
PA5-11438
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 298-328 amino acids from the C-terminal region of human GATA4
Conjugate
Form
Liquid
Concentration
2.0 mg/mL
Purification
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2108596
Product Specific Information
This antibody is predicted to react with mouse, rat and Xenopus based on sequence homology.
Target Information
GATA4 is a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in the gene encoding GATA4 have been associated with cardiac septal defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GAT4; GATA-binding factor 4; MGC126629; Transcription factor GATA-4
Gene Aliases: ASD2; GATA4; TACHD; TOF; VSD1
UniProt ID: (Human) P43694
Entrez Gene ID: (Human) 2626
RNA polymerase II regulatory region sequence-specific DNA binding
transcription factor activity, RNA polymerase II transcription factor binding
RNA polymerase II transcription factor binding
enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
transcription factor binding
zinc ion binding
protein kinase binding
activating transcription factor binding
sequence-specific DNA binding
transcription regulatory region DNA binding
NFAT protein binding
co-SMAD binding
DNA-binding transcription factor
heart looping
endocardial cushion development
cardiac ventricle morphogenesis
cardiac right ventricle morphogenesis
ventricular septum development
atrial septum primum morphogenesis
atrial septum secundum morphogenesis
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
cell-cell signaling
endoderm development
blood coagulation
male gonad development
response to mechanical stimulus
negative regulation of autophagy
positive regulation of vascular endothelial growth factor production
positive regulation of BMP signaling pathway
response to vitamin A
embryonic heart tube anterior/posterior pattern specification
response to drug
cell fate commitment
positive regulation of angiogenesis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cell development
embryonic foregut morphogenesis
anatomical structure formation involved in morphogenesis
positive regulation of cardioblast differentiation
transdifferentiation
atrial septum morphogenesis
intestinal epithelial cell differentiation
cell growth involved in cardiac muscle cell development
cellular response to glucose stimulus
regulation of cardiac muscle cell contraction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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