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Product Details
H00002626-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
6C6
Immunogen
GATA4 (NP_002043.2, 343 a.a. approximately 442 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: ASGASSNSSN ATTSSSEEMR PIKTEPGLSS HYGHSSSVSQ TFSVSAMSGH GPSIHPVLSA LKLSPQGYAS PVSQSPQTSS KQDSWNSLVL ADSHGDIITA
Target Information
GATA4 is a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in the gene encoding GATA4 have been associated with cardiac septal defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GAT4; GATA-binding factor 4; MGC126629; Transcription factor GATA-4
Gene Aliases: ASD2; GATA4; TACHD; TOF; VSD1
UniProt ID: (Human) P43694
Entrez Gene ID: (Human) 2626
RNA polymerase II regulatory region sequence-specific DNA binding
transcription factor activity, RNA polymerase II transcription factor binding
RNA polymerase II transcription factor binding
enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
transcription factor binding
zinc ion binding
protein kinase binding
activating transcription factor binding
sequence-specific DNA binding
transcription regulatory region DNA binding
NFAT protein binding
co-SMAD binding
DNA-binding transcription factor
heart looping
endocardial cushion development
cardiac ventricle morphogenesis
cardiac right ventricle morphogenesis
ventricular septum development
atrial septum primum morphogenesis
atrial septum secundum morphogenesis
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
cell-cell signaling
endoderm development
blood coagulation
male gonad development
response to mechanical stimulus
negative regulation of autophagy
positive regulation of vascular endothelial growth factor production
positive regulation of BMP signaling pathway
response to vitamin A
embryonic heart tube anterior/posterior pattern specification
response to drug
cell fate commitment
positive regulation of angiogenesis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cell development
embryonic foregut morphogenesis
anatomical structure formation involved in morphogenesis
positive regulation of cardioblast differentiation
transdifferentiation
atrial septum morphogenesis
intestinal epithelial cell differentiation
cell growth involved in cardiac muscle cell development
cellular response to glucose stimulus
regulation of cardiac muscle cell contraction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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