Product References
Rapamycin Inhibits Osteoclastogenesis and Prevents LPS-Induced Alveolar Bone Loss by Oxidative Stress Suppression.
ACS omega
Feng C,Liu Y,Zhang BY,Zhang H,Shan FY,Li TQ,Zhao ZN,Wang XX,Zhang XY
Tue Jun 13 00:00:00 EDT 2023
Sulforaphane prevents LPS-induced inflammation by regulating the Nrf2-mediated autophagy pathway in goat mammary epithelial cells and a mouse model of mastitis.
Journal of animal science and biotechnology
Shao D,Shen W,Miao Y,Gao Z,Pan M,Wei Q,Yan Z,Zhao X,Ma B
Wed May 03 00:00:00 EDT 2023
Inula japonica ameliorated the inflammation and oxidative stress in LPS-induced acute lung injury through the MAPK/NF-κB and Keap1/Nrf2 signalling pathways.
The Journal of pharmacy and pharmacology
Zhang M,Zhang J,Zhu QM,Zhao WY,Lv X,Yi J,Huo XK,Wang MJ,Sun CP
Wed Feb 08 00:00:00 EST 2023
Aescin can alleviate NAFLD through Keap1-Nrf2 by activating antioxidant and autophagy.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Yu H,Yan S,Jin M,Wei Y,Zhao L,Cheng J,Ding L,Feng H
Mon May 01 00:00:00 EDT 2023
Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury.
ACS central science
Zhang J,Zhang M,Huo XK,Ning J,Yu ZL,Morisseau C,Sun CP,Hammock BD,Ma XC
Wed Mar 22 00:00:00 EDT 2023
Human hematopoietic stem cell vulnerability to ferroptosis.
Cell
Zhao J,Jia Y,Mahmut D,Deik AA,Jeanfavre S,Clish CB,Sankaran VG
Thu Feb 16 00:00:00 EST 2023
Single-cell transcriptomes reveal heterogeneity of chlorine-induced mice acute lung injury and the inhibitory effect of pentoxifylline on ferroptosis.
Scientific reports
Zhao CQ,Wang C,Liu MM,Cao M,Peng J,Kong DQ,Ren XT,Liu R,Hai CX,Zhang XD
Wed Apr 26 00:00:00 EDT 2023
A small-molecule inhibitor of Keap1-Nrf2 interaction attenuates sepsis by selectively augmenting the antibacterial defence of macrophages at infection sites.
EBioMedicine
Wang Y,Tang B,Li H,Zheng J,Zhang C,Yang Z,Tan X,Luo P,Ma L,Wang Y,Long L,Chen Z,Xiao Z,Ma L,Zhou J,Wang Y,Shi C
Sat Apr 01 00:00:00 EDT 2023
Increased glucose availability sensitizes pancreatic cancer to chemotherapy.
Nature communications
Vaziri-Gohar A,Hue JJ,Abbas A,Graor HJ,Hajihassani O,Zarei M,Titomihelakis G,Feczko J,Rathore M,Chelstowska S,Loftus AW,Wang R,Zarei M,Goudarzi M,Zhang R,Willard B,Zhang L,Kresak A,Willis JE,Wang GM,Tatsuoka C,Salvino JM,Bederman I,Brunengraber H,Lyssiotis CA,Brody JR,Winter JM
Wed Jun 28 00:00:00 EDT 2023
Increased glucose availability sensitizes pancreatic cancer to chemotherapy.
Nature communications
Vaziri-Gohar A,Hue JJ,Abbas A,Graor HJ,Hajihassani O,Zarei M,Titomihelakis G,Feczko J,Rathore M,Chelstowska S,Loftus AW,Wang R,Zarei M,Goudarzi M,Zhang R,Willard B,Zhang L,Kresak A,Willis JE,Wang GM,Tatsuoka C,Salvino JM,Bederman I,Brunengraber H,Lyssiotis CA,Brody JR,Winter JM
Wed Jun 28 00:00:00 EDT 2023
Dihydromyricetin attenuates cisplatin-induced acute kidney injury by reducing oxidative stress, inflammation and ferroptosis.
Toxicology and applied pharmacology
Xu Z,Zhang M,Wang W,Zhou S,Yu M,Qiu X,Jiang S,Wang X,Tang C,Li S,Wang CH,Zhu R,Peng WX,Zhao L,Fu X,Patzak A,Persson PB,Zhao L,Mao J,Shu Q,Lai EY,Zhang G
Tue Aug 15 00:00:00 EDT 2023
Combination with vorinostat enhances the antitumor activity of cisplatin in castration-resistant prostate cancer by inhibiting DNA damage repair pathway and detoxification of GSH.
The Prostate
Chang T,Lian Z,Ma S,Liang Z,Ma X,Wen X,Wang Y,Liu R
Sat Apr 01 00:00:00 EDT 2023
Sulforaphane Suppresses H2O2-Induced Oxidative Stress and Apoptosis via the Activation of AMPK/NFE2L2 Signaling Pathway in Goat Mammary Epithelial Cells.
International journal of molecular sciences
Shao D,Gao Z,Zhao Y,Fan M,Zhao X,Wei Q,Pan M,Ma B
Thu Jan 05 00:00:00 EST 2023
ARE-PROTACs Enable Co-degradation of an Nrf2-MafG Heterodimer.
Journal of medicinal chemistry
Ji J,Ma S,Zhu Y,Zhao J,Tong Y,You Q,Jiang Z
Thu May 11 00:00:00 EDT 2023
α-Cyperone protects dopaminergic neurons and inhibits neuroinflammation in LPS-induced Parkinson's disease rat model via activating Nrf2/HO-1 and suppressing NF-κB signaling pathway.
International immunopharmacology
Huang B,Hu G,Zong X,Yang S,He D,Gao X,Liu D
Wed Feb 01 00:00:00 EST 2023
Inhibition of ferroptosis attenuates oligospermia in male Nrf2 knockout mice.
Free radical biology & medicine
Han P,Wang X,Zhou T,Cheng J,Wang C,Sun F,Zhao X
Sun Nov 20 00:00:00 EST 2022
Total flavonoids of Inula japonica alleviated the inflammatory response and oxidative stress in LPS-induced acute lung injury via inhibiting the sEH activity: Insights from lipid metabolomics.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhang J,Zhang M,Zhang WH,Zhu QM,Huo XK,Sun CP,Ma XC,Xiao HT
Thu Dec 01 00:00:00 EST 2022
Protective Effect of Danshen Zexie Decoction Against Non-Alcoholic Fatty Liver Disease Through Inhibition of ROS/NLRP3/IL-1β Pathway by Nrf2 Signaling Activation.
Frontiers in pharmacology
Biao Y,Chen J,Liu C,Wang R,Han X,Li L,Zhang Y
Sat Jul 16 00:00:00 EDT 2022
Acute lung inflammation induced by zinc oxide nanoparticles: Evolution and intervention via NRF2 activator.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Guo T,Fang X,Liu Y,Ruan Y,Hu Y,Wang X,Hu Y,Wang G,Xu Y
Fri Apr 01 00:00:00 EDT 2022
Nrf2 Signaling Pathway Mediates the Protective Effects of Daphnetin Against D-Galactose Induced-Premature Ovarian Failure.
Frontiers in pharmacology
Zhang M,Yu X,Li D,Ma N,Wei Z,Ci X,Zhang S
Wed Feb 16 00:00:00 EST 2022
Glucose-6-phosphate dehydrogenase exerts antistress effects independently of its enzymatic activity.
The Journal of biological chemistry
Jin X,Li X,Li L,Zhong B,Hong Y,Niu J,Li B
Thu Dec 01 00:00:00 EST 2022
Psoralen alleviates radiation-induced bone injury by rescuing skeletal stem cell stemness through AKT-mediated upregulation of GSK-3β and NRF2.
Stem cell research & therapy
Yin BF,Li ZL,Yan ZQ,Guo Z,Liang JW,Wang Q,Zhao ZD,Li PL,Hao RC,Han MY,Li XT,Mao N,Ding L,Chen DF,Gao Y,Zhu H
Tue Jun 07 00:00:00 EDT 2022
PrPSc Inhibition and Cellular Protection of DBL on a Prion-Infected Cultured Cell via Multiple Pathways.
Molecular neurobiology
Yang W,Chen C,Chen J,Xia Y,Hu C,Wang L,Wu YZ,Shi Q,Chen ZB,Dong XP
Sun May 01 00:00:00 EDT 2022
Total terpenoids of Inula japonica activated the Nrf2 receptor to alleviate the inflammation and oxidative stress in LPS-induced acute lung injury.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhang J,Zhang M,Zhang WH,Zhu QM,Ning J,Huo XK,Xiao HT,Sun CP
Thu Dec 01 00:00:00 EST 2022
Antagonistic effects of selenium on lead-induced oxidative stress and apoptosis of Leydig cells in sheep.
Theriogenology
Shi L,Wang X,Duan Y,Li K,Ren Y
Wed Jun 01 00:00:00 EDT 2022
A comparison study between dimethyl itaconate and dimethyl fumarate in electrophilicity, Nrf2 activation, and anti-inflammation in vitro.
Journal of Asian natural products research
Zhang Y,Zhou YJ,Tang JS,Lan JQ,Kang YY,Wu L,Peng Y
Wed Jun 01 00:00:00 EDT 2022
Dihydroartemisinin enhances the inhibitory effect of sorafenib on HepG2 cells by inducing ferroptosis and inhibiting energy metabolism.
Journal of pharmacological sciences
Cui Z,Wang H,Li S,Qin T,Shi H,Ma J,Li L,Yu G,Jiang T,Li C
Sat Jan 01 00:00:00 EST 2022
Downregulation of CD151 induces oxidative stress and apoptosis in trophoblast cells via inhibiting ERK/Nrf2 signaling pathway in preeclampsia.
Free radical biology & medicine
Wang Z,Cai B,Cao C,Lv H,Dai Y,Zheng M,Zhao G,Peng Y,Gou W,Wang J,Liu D,Hu Y
Sat Feb 20 00:00:00 EST 2021
USP15 participates in DBP-induced testicular oxidative stress injury through regulating the Keap1/Nrf2 signaling pathway.
The Science of the total environment
Zhang L,Gao X,Qin Z,Shi X,Xu K,Wang S,Tang M,Wang W,Gao S,Zuo L,Zhang L,Zhang W
Fri Aug 20 00:00:00 EDT 2021
Phytochemical characterization and hepatoprotective effect of active fragment from Adhatoda vasica Nees. against tert-butyl hydroperoxide induced oxidative impairment via activating AMPK/p62/Nrf2 pathway.
Journal of ethnopharmacology
Lu Q,Gu W,Luo C,Wang L,Hua W,Sun Y,Tang L
Wed Feb 10 00:00:00 EST 2021
Neuroprotective Effects and Mechanisms of Procyanidins In Vitro and In Vivo.
Molecules (Basel, Switzerland)
Chen J,Chen Y,Zheng Y,Zhao J,Yu H,Zhu J,Li D
Mon May 17 00:00:00 EDT 2021
Lycium barbarum polysaccharides attenuate cardiovascular oxidative stress injury by enhancing the Keap1/Nrf2 signaling pathway in exhaustive exercise rats.
Molecular medicine reports
Hu X,Mu L,Zhu L,Chang X,Nie L,Wang L,Li G
Wed Sep 01 00:00:00 EDT 2021
Lycium barbarum polysaccharides attenuate cardiovascular oxidative stress injury by enhancing the Keap1/Nrf2 signaling pathway in exhaustive exercise rats.
Molecular medicine reports
Hu X,Mu L,Zhu L,Chang X,Nie L,Wang L,Li G
Wed Sep 01 00:00:00 EDT 2021
Mechanistic Analysis of an Extracellular Signal-Regulated Kinase 2-Interacting Compound that Inhibits Mutant BRAF-Expressing Melanoma Cells by Inducing Oxidative Stress.
The Journal of pharmacology and experimental therapeutics
Martinez R,Huang W,Samadani R,Mackowiak B,Centola G,Chen L,Conlon IL,Hom K,Kane MA,Fletcher S,Shapiro P
Fri Jan 01 00:00:00 EST 2021
Loss of QKI in macrophage aggravates inflammatory bowel disease through amplified ROS signaling and microbiota disproportion.
Cell death discovery
Wang W,Zhai D,Bai Y,Xue K,Deng L,Ma L,Du T,Ye Z,Qu D,Xiang A,Chen G,Zhao Y,Wang L,Lu Z
Tue Mar 23 00:00:00 EDT 2021
SLC7A11 Reduces Laser-Induced Choroidal Neovascularization by Inhibiting RPE Ferroptosis and VEGF Production.
Frontiers in cell and developmental biology
Zhao X,Gao M,Liang J,Chen Y,Wang Y,Wang Y,Xiao Y,Zhao Z,Wan X,Jiang M,Luo X,Wang F,Sun X
Wed Mar 10 00:00:00 EST 2021
Tangeretin maintains antioxidant activity by reducing CUL3 mediated NRF2 ubiquitination.
Food chemistry
Wang Y,Jin R,Chen J,Cao J,Xiao J,Li X,Sun C
Wed Dec 15 00:00:00 EST 2021
The novel nanocomplexes containing deoxycholic acid-grafted chitosan and oleanolic acid displays the hepatoprotective effect against CCl4-induced liver injury in vivo.
International journal of biological macromolecules
Xin C,Liu S,Qu H,Wang Z
Tue Aug 31 00:00:00 EDT 2021
Protective Effects and Mechanisms of Procyanidins on Parkinson's Disease In Vivo and In Vitro.
Molecules (Basel, Switzerland)
Chen J,Chen Y,Zheng Y,Zhao J,Yu H,Zhu J,Li D
Mon Sep 13 00:00:00 EDT 2021
Effects of β-Asarone on Ischemic Stroke in Middle Cerebral Artery Occlusion Rats by an Nrf2-Antioxidant Response Elements (ARE) Pathway-Dependent Mechanism.
Medical science monitor : international medical journal of experimental and clinical research
Pan H,Xu Y,Cai Q,Wu M,Ding M
Fri Jun 04 00:00:00 EDT 2021
hPMSCs inhibit the expression of PD-1 in CD4+IL-10+ T cells and mitigate liver damage in a GVHD mouse model by regulating the crosstalk between Nrf2 and NF-κB signaling pathway.
Stem cell research & therapy
Zhang A,Zhang J,Li X,Zhang H,Xiong Y,Wang Z,Zhao N,Wang F,Luan X
Tue Jun 29 00:00:00 EDT 2021
Polyphenols from Penthorum chinense Pursh. Attenuates high glucose-induced vascular inflammation through directly interacting with Keap1 protein.
Journal of ethnopharmacology
Sun Y,He L,Wang W,Wang T,Hua W,Li T,Wang L,Gao T,Chen F,Tang L
Thu Mar 25 00:00:00 EDT 2021
Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response.
International immunopharmacology
Wang L,Wang X,Kong L,Wang S,Huang K,Wu J,Wang C,Sun H,Liu K,Meng Q
Mon Nov 01 00:00:00 EDT 2021
Nfe2l1 deficiency mitigates streptozotocin-induced pancreatic β-cell destruction and development of diabetes in male mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Bao S,Zheng H,Chen C,Zhang Y,Bao L,Yang B,Hou Y,Chen Y,Zhang Q,Pi J,Fu J
Wed Dec 01 00:00:00 EST 2021
Alpinetin exerts anti-inflammatory, anti-oxidative and anti-angiogenic effects through activating the Nrf2 pathway and inhibiting NLRP3 pathway in carbon tetrachloride-induced liver fibrosis.
International immunopharmacology
Zhu Z,Hu R,Li J,Xing X,Chen J,Zhou Q,Sun J
Thu Jul 01 00:00:00 EDT 2021
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.
Nature cell biology
Shi M,Huang XY,Ren XY,Wei XY,Ma Y,Lin ZZ,Liu DT,Song L,Zhao TJ,Li G,Yao L,Zhu M,Zhang C,Xie C,Wu Y,Wu HM,Fan LP,Ou J,Zhan YH,Lin SY,Lin SC
Mon Mar 01 00:00:00 EST 2021
RPRD1A stabilizes NRF2 and aggravates HCC progression through competing with p62 for TRIM21 binding.
Cell death & disease
Feng X,Jiang T,Yang C,Pang S,Ding Z,Hu H,Wang H,Dong L,Yang N
Fri Dec 17 00:00:00 EST 2021
SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells.
Nature
Wang Y,Yen FS,Zhu XG,Timson RC,Weber R,Xing C,Liu Y,Allwein B,Luo H,Yeh HW,Heissel S,Unlu G,Gamazon ER,Kharas MG,Hite R,Birsoy K
Mon Nov 01 00:00:00 EDT 2021
H2S improves doxorubicin-induced myocardial fibrosis by inhibiting oxidative stress and apoptosis via Keap1-Nrf2.
Technology and health care : official journal of the European Society for Engineering and Medicine
Li Y,Chandra TP,Song X,Nie L,Liu M,Yi J,Zheng X,Chu C,Yang J
Wed Aug 18 00:00:00 EDT 2021
Farrerol Enhances Nrf2-Mediated Defense Mechanisms against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial Cells by Activating Akt and MAPK.
Oxidative medicine and cellular longevity
Ma N,Yang X,Qi C,Yu Q,Zhu C,Ren H
Wed May 19 00:00:00 EDT 2021
Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress.
Frontiers in molecular biosciences
Fu N,Li D,Li W,Zhao W,Zhang S,Liu L,Zhao S,Du J,Kong L,Wang R,Zhang Y,Nan Y
Tue Oct 06 00:00:00 EDT 2020
Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress.
Frontiers in molecular biosciences
Fu N,Li D,Li W,Zhao W,Zhang S,Liu L,Zhao S,Du J,Kong L,Wang R,Zhang Y,Nan Y
Tue Oct 06 00:00:00 EDT 2020
Chronic toxicity of methamphetamine: Oxidative remodeling of pulmonary arteries.
Toxicology in vitro : an international journal published in association with BIBRA
Liang LY,Wang MM,Liu M,Zhao W,Wang X,Shi L,Zhu MJ,Zhao YL,Liu L,Maurya P,Wang Y
Sat Feb 01 00:00:00 EST 2020
Resveratrol protects the integrity of alveolar epithelial barrier via SIRT1/PTEN/p-Akt pathway in methamphetamine-induced chronic lung injury.
Cell proliferation
Wang X,Liu M,Zhu MJ,Shi L,Liu L,Zhao YL,Cheng L,Gu YJ,Zhou MY,Chen L,Kumar A,Wang Y
Sun Mar 01 00:00:00 EST 2020
Fasting Induces Hepatocellular Carcinoma Cell Apoptosis by Inhibiting SET8 Expression.
Oxidative medicine and cellular longevity
Qi J,Chen X,Wu Q,Wang J,Zhang H,Mao A,Zhu M,Miao C
Tue Nov 17 00:00:00 EST 2020
RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury.
Cell stress & chaperones
Shi L,Liu BY,Wang X,Zhu MJ,Chen L,Zhou MY,Gu YJ,Cheng L,Wang Y
Tue Sep 01 00:00:00 EDT 2020
Exposure of Rats to Multiple Oral Doses of Dichloroacetate Results in Upregulation of Hepatic Glutathione Transferases and NAD(P)H Dehydrogenase [Quinone] 1.
Drug metabolism and disposition: the biological fate of chemicals
Squirewell EJ,Mareus R,Horne LP,Stacpoole PW,James MO
Sun Nov 01 00:00:00 EDT 2020
Autophagy inducer activates Nrf2-ARE pathway to attenuate aberrant alveolarization in neonatal rats with bronchopulmonary dysplasia.
Life sciences
Zhao X,Shi Y,Zhang D,Tong X,Sun Y,Xue X,Fu J
Wed Jul 01 00:00:00 EDT 2020
Autophagy inducer activates Nrf2-ARE pathway to attenuate aberrant alveolarization in neonatal rats with bronchopulmonary dysplasia.
Life sciences
Zhao X,Shi Y,Zhang D,Tong X,Sun Y,Xue X,Fu J
Wed Jul 01 00:00:00 EDT 2020
Pyridoxine induces glutathione synthesis via PKM2-mediated Nrf2 transactivation and confers neuroprotection.
Nature communications
Wei Y,Lu M,Mei M,Wang H,Han Z,Chen M,Yao H,Song N,Ding X,Ding J,Xiao M,Hu G
Tue Feb 18 00:00:00 EST 2020
Rice Protein Exerts Endogenous Antioxidant Capacity via Methionine Sulfoxide Reductase and the Nrf2 Antioxidant System Independent of Age.
Journal of medicinal food
Li H,Liang M,Wang Z,Zhang Y,Wu Q,Yang L
Mon Jun 01 00:00:00 EDT 2020
Lysosome-associated membrane protein-2 deficiency increases the risk of reactive oxygen species-induced ferroptosis in retinal pigment epithelial cells.
Biochemical and biophysical research communications
Lee JJ,Ishihara K,Notomi S,Efstathiou NE,Ueta T,Maidana D,Chen X,Iesato Y,Caligiana A,Vavvas DG
Wed Jan 08 00:00:00 EST 2020
Computational repositioning of dimethyl fumarate for treating alcoholic liver disease.
Cell death & disease
Zhang Y,Zhao S,Fu Y,Yan L,Feng Y,Chen Y,Wu Y,Deng Y,Zhang G,Chen Z,Chen Y,Liu T
Tue Aug 18 00:00:00 EDT 2020
High glucose inhibits vascular endothelial Keap1/Nrf2/ARE signal pathway via downregulation of monomethyltransferase SET8 expression.
Acta biochimica et biophysica Sinica
Chen X,Qi J,Wu Q,Jiang H,Wang J,Chen W,Mao A,Zhu M
Tue May 26 00:00:00 EDT 2020
Rice protein stimulates endogenous antioxidant response attributed to methionine availability in growing rats.
Journal of food biochemistry
Wang Z,Cai L,Li H,Liang M,Zhang Y,Wu Q,Yang L
Fri May 01 00:00:00 EDT 2020
FSHR ablation induces depression-like behaviors.
Acta pharmacologica Sinica
Bi WK,Shao SS,Li ZW,Ruan YW,Luan SS,Dong ZH,Wang J,Wu SS,Guo T,Ma SZ,Gao L,Zhao JJ,He Z
Sat Aug 01 00:00:00 EDT 2020
Overexpression of NRF1-742 or NRF1-772 Reduces Arsenic-Induced Cytotoxicity and Apoptosis in Human HaCaT Keratinocytes.
International journal of molecular sciences
Wang S,Cheng H,Wang L,Zhao R,Guan D
Mon Mar 16 00:00:00 EDT 2020
Effect of DJ-1 on the neuroprotection of astrocytes subjected to cerebral ischemia/reperfusion injury.
Journal of molecular medicine (Berlin, Germany)
Peng L,Zhao Y,Li Y,Zhou Y,Li L,Lei S,Yu S,Zhao Y
Fri Feb 01 00:00:00 EST 2019
Effect of DJ-1 on the neuroprotection of astrocytes subjected to cerebral ischemia/reperfusion injury.
Journal of molecular medicine (Berlin, Germany)
Peng L,Zhao Y,Li Y,Zhou Y,Li L,Lei S,Yu S,Zhao Y
Fri Feb 01 00:00:00 EST 2019
Size and temporal-dependent efficacy of oltipraz-loaded PLGA nanoparticles for treatment of acute kidney injury and fibrosis.
Biomaterials
Yu H,Lin T,Chen W,Cao W,Zhang C,Wang T,Ding M,Zhao S,Wei H,Guo H,Zhao X
Tue Oct 01 00:00:00 EDT 2019
SIRT2, ERK and Nrf2 Mediate NAD+ Treatment-Induced Increase in the Antioxidant Capacity of PC12 Cells Under Basal Conditions.
Frontiers in molecular neuroscience
Zhang J,Hong Y,Cao W,Yin S,Shi H,Ying W
Wed Sep 30 00:00:00 EDT 2020
Induction of Nrf2 pathway by Dendrobium nobile Lindl. alkaloids protects against carbon tetrachloride induced acute liver injury.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Li S,Zhou J,Xu S,Li J,Liu J,Lu Y,Shi J,Zhou S,Wu Q
Sun Sep 01 00:00:00 EDT 2019
Disubstituted Dithiolethione ACDT Exerts Neuroprotective Effects Against 6-Hydroxydopamine-Induced Oxidative Stress in SH-SY5Y Cells.
Neurochemical research
Betharia S,Rondόn-Ortiz AN,Brown DA
Thu Aug 01 00:00:00 EDT 2019
Cordycepin prevents radiation ulcer by inhibiting cell senescence via NRF2 and AMPK in rodents.
Nature communications
Wang Z,Chen Z,Jiang Z,Luo P,Liu L,Huang Y,Wang H,Wang Y,Long L,Tan X,Liu D,Jin T,Wang Y,Wang Y,Liao F,Zhang C,Chen L,Gan Y,Liu Y,Yang F,Huang C,Miao H,Chen J,Cheng T,Fu X,Shi C
Mon Jun 10 00:00:00 EDT 2019
[Effect of hyperoxic exposure on the expression of heme oxygenase-1 and glutamate-L-cysteine ligase catalytic subunit in lung tissue of preterm rats].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
Chu XY,Cai C,Zhang XY,Zhou HL,Sun JF,Weng BW
Sat Jun 01 00:00:00 EDT 2019
Branched-Chain Amino Acid Metabolic Reprogramming Orchestrates Drug Resistance to EGFR Tyrosine Kinase Inhibitors.
Cell reports
Wang Y,Zhang J,Ren S,Sun D,Huang HY,Wang H,Jin Y,Li F,Zheng C,Yang L,Deng L,Jiang Z,Jiang T,Han X,Hou S,Guo C,Li F,Gao D,Qin J,Gao D,Chen L,Lin SH,Wong KK,Li C,Hu L,Zhou C,Ji H
Tue Jul 09 00:00:00 EDT 2019
γ-Oryzanol alleviates acetaminophen-induced liver injury: roles of modulating AMPK/GSK3β/Nrf2 and NF-κB signaling pathways.
Food & function
Shu G,Qiu Y,Hao J,Fu Q,Deng X
Wed Oct 16 00:00:00 EDT 2019
Characterization of natural melanin from Auricularia auricula and its hepatoprotective effect on acute alcohol liver injury in mice.
Food & function
Hou R,Liu X,Yan J,Xiang K,Wu X,Lin W,Chen G,Zheng M,Fu J
Wed Feb 20 00:00:00 EST 2019
Phytochemical composition, isolation and hepatoprotective activity of active fraction from Veronica ciliata against acetaminophen-induced acute liver injury via p62-Keap1-Nrf2 signaling pathway.
Journal of ethnopharmacology
Lu Q,Tan S,Gu W,Li F,Hua W,Zhang S,Chen F,Tang L
Mon Oct 28 00:00:00 EDT 2019
l-Methionine activates Nrf2-ARE pathway to induce endogenous antioxidant activity for depressing ROS-derived oxidative stress in growing rats.
Journal of the science of food and agriculture
Wang Z,Liang M,Li H,Cai L,He H,Wu Q,Yang L
Thu Aug 15 00:00:00 EDT 2019
Orthoxenografts of Testicular Germ Cell Tumors Demonstrate Genomic Changes Associated with Cisplatin Resistance and Identify PDMP as a Resensitizing Agent.
Clinical cancer research : an official journal of the American Association for Cancer Research
Piulats JM,Vidal A,García-Rodríguez FJ,Muñoz C,Nadal M,Moutinho C,Martínez-Iniesta M,Mora J,Figueras A,Guinó E,Padullés L,Aytés À,Molleví DG,Puertas S,Martínez-Fernández C,Castillo W,Juliachs M,Moreno V,Muñoz P,Stefanovic M,Pujana MA,Condom E,Esteller M,Germà JR,Capella G,Farré L,Morales A,Viñals F,García-Del-Muro X,Cerón J,Villanueva A
Wed Aug 01 00:00:00 EDT 2018
Orthoxenografts of Testicular Germ Cell Tumors Demonstrate Genomic Changes Associated with Cisplatin Resistance and Identify PDMP as a Resensitizing Agent.
Clinical cancer research : an official journal of the American Association for Cancer Research
Piulats JM,Vidal A,García-Rodríguez FJ,Muñoz C,Nadal M,Moutinho C,Martínez-Iniesta M,Mora J,Figueras A,Guinó E,Padullés L,Aytés À,Molleví DG,Puertas S,Martínez-Fernández C,Castillo W,Juliachs M,Moreno V,Muñoz P,Stefanovic M,Pujana MA,Condom E,Esteller M,Germà JR,Capella G,Farré L,Morales A,Viñals F,García-Del-Muro X,Cerón J,Villanueva A
Wed Aug 01 00:00:00 EDT 2018
Progesterone maintains the status of granulosa cells and slows follicle development partly through PGRMC1.
Journal of cellular physiology
Yuan XH,Yang CR,Wang XN,Zhang LL,Gao XR,Shi ZY
Mon Jan 01 00:00:00 EST 2018
Progesterone maintains the status of granulosa cells and slows follicle development partly through PGRMC1.
Journal of cellular physiology
Yuan XH,Yang CR,Wang XN,Zhang LL,Gao XR,Shi ZY
Mon Jan 01 00:00:00 EST 2018
Activation of Nrf2 pathway and inhibition of NLRP3 inflammasome activation contribute to the protective effect of chlorogenic acid on acute liver injury.
International immunopharmacology
Shi A,Shi H,Wang Y,Liu X,Cheng Y,Li H,Zhao H,Wang S,Dong L
Mon Jan 01 00:00:00 EST 2018
Activation of Nrf2 pathway and inhibition of NLRP3 inflammasome activation contribute to the protective effect of chlorogenic acid on acute liver injury.
International immunopharmacology
Shi A,Shi H,Wang Y,Liu X,Cheng Y,Li H,Zhao H,Wang S,Dong L
Mon Jan 01 00:00:00 EST 2018
l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Liang M,Wang Z,Li H,Cai L,Pan J,He H,Wu Q,Tang Y,Ma J,Yang L
Tue May 01 00:00:00 EDT 2018
l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Liang M,Wang Z,Li H,Cai L,Pan J,He H,Wu Q,Tang Y,Ma J,Yang L
Tue May 01 00:00:00 EDT 2018
2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone, a potent Nrf2/ARE pathway inhibitor, reverses drug resistance by decreasing glutathione synthesis and drug efflux in BEL-7402/5-FU cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Wei X,Mo X,An F,Ji X,Lu Y
Sat Sep 01 00:00:00 EDT 2018
2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone, a potent Nrf2/ARE pathway inhibitor, reverses drug resistance by decreasing glutathione synthesis and drug efflux in BEL-7402/5-FU cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Wei X,Mo X,An F,Ji X,Lu Y
Sat Sep 01 00:00:00 EDT 2018
Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.
Regulatory toxicology and pharmacology : RTP
Ning C,Gao X,Wang C,Kong Y,Liu Z,Sun H,Sun P,Huo X,Ma X,Meng Q,Liu K
Mon Oct 01 00:00:00 EDT 2018
Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.
Regulatory toxicology and pharmacology : RTP
Ning C,Gao X,Wang C,Kong Y,Liu Z,Sun H,Sun P,Huo X,Ma X,Meng Q,Liu K
Mon Oct 01 00:00:00 EDT 2018
Liver-specific deficiency of unc-51 like kinase 1 and 2 protects mice from acetaminophen-induced liver injury.
Hepatology (Baltimore, Md.)
Sun Y,Li TY,Song L,Zhang C,Li J,Lin ZZ,Lin SC,Lin SY
Fri Jun 01 00:00:00 EDT 2018
Ltbp4 regulates Pdgfrβ expression via TGFβ-dependent modulation of Nrf2 transcription factor function.
Matrix biology : journal of the International Society for Matrix Biology
Tomasovic A,Kurrle N,Wempe F,De-Zolt S,Scheibe S,Koli K,Serchinger M,Schnütgen F,Sürün D,Sterner-Kock A,Weissmann N,von Melchner H
Mon May 01 00:00:00 EDT 2017
Ltbp4 regulates Pdgfrβ expression via TGFβ-dependent modulation of Nrf2 transcription factor function.
Matrix biology : journal of the International Society for Matrix Biology
Tomasovic A,Kurrle N,Wempe F,De-Zolt S,Scheibe S,Koli K,Serchinger M,Schnütgen F,Sürün D,Sterner-Kock A,Weissmann N,von Melchner H
Mon May 01 00:00:00 EDT 2017
An inducible form of Nrf2 confers enhanced protection against acute oxidative stresses in RPE cells.
Experimental eye research
Vu KT,Hulleman JD
Wed Nov 01 00:00:00 EDT 2017
An inducible form of Nrf2 confers enhanced protection against acute oxidative stresses in RPE cells.
Experimental eye research
Vu KT,Hulleman JD
Wed Nov 01 00:00:00 EDT 2017
Mitochondrial DNA Replication Defects Disturb Cellular dNTP Pools and Remodel One-Carbon Metabolism.
Cell metabolism
Nikkanen J,Forsström S,Euro L,Paetau I,Kohnz RA,Wang L,Chilov D,Viinamäki J,Roivainen A,Marjamäki P,Liljenbäck H,Ahola S,Buzkova J,Terzioglu M,Khan NA,Pirnes-Karhu S,Paetau A,Lönnqvist T,Sajantila A,Isohanni P,Tyynismaa H,Nomura DK,Battersby BJ,Velagapudi V,Carroll CJ,Suomalainen A
Tue Apr 12 00:00:00 EDT 2016
Mitochondrial DNA Replication Defects Disturb Cellular dNTP Pools and Remodel One-Carbon Metabolism.
Cell metabolism
Nikkanen J,Forsström S,Euro L,Paetau I,Kohnz RA,Wang L,Chilov D,Viinamäki J,Roivainen A,Marjamäki P,Liljenbäck H,Ahola S,Buzkova J,Terzioglu M,Khan NA,Pirnes-Karhu S,Paetau A,Lönnqvist T,Sajantila A,Isohanni P,Tyynismaa H,Nomura DK,Battersby BJ,Velagapudi V,Carroll CJ,Suomalainen A
Tue Apr 12 00:00:00 EDT 2016
Progesterone amplifies oxidative stress signal and promotes NO production via H2O2 in mouse kidney arterial endothelial cells.
The Journal of steroid biochemistry and molecular biology
Yuan XH,Fan YY,Yang CR,Gao XR,Zhang LL,Hu Y,Wang YQ,Jun H
Fri Jan 01 00:00:00 EST 2016
Progesterone amplifies oxidative stress signal and promotes NO production via H2O2 in mouse kidney arterial endothelial cells.
The Journal of steroid biochemistry and molecular biology
Yuan XH,Fan YY,Yang CR,Gao XR,Zhang LL,Hu Y,Wang YQ,Jun H
Fri Jan 01 00:00:00 EST 2016
SIRT2 mediates NADH-induced increases in Nrf2, GCL, and glutathione by modulating Akt phosphorylation in PC12 cells.
FEBS letters
Cao W,Hong Y,Chen H,Wu F,Wei X,Ying W
Fri Jul 01 00:00:00 EDT 2016
SIRT2 mediates NADH-induced increases in Nrf2, GCL, and glutathione by modulating Akt phosphorylation in PC12 cells.
FEBS letters
Cao W,Hong Y,Chen H,Wu F,Wei X,Ying W
Fri Jul 01 00:00:00 EDT 2016
The Essential Role of H19 Contributing to Cisplatin Resistance by Regulating Glutathione Metabolism in High-Grade Serous Ovarian Cancer.
Scientific reports
Zheng ZG,Xu H,Suo SS,Xu XL,Ni MW,Gu LH,Chen W,Wang LY,Zhao Y,Tian B,Hua YJ
Thu May 19 00:00:00 EDT 2016
The Essential Role of H19 Contributing to Cisplatin Resistance by Regulating Glutathione Metabolism in High-Grade Serous Ovarian Cancer.
Scientific reports
Zheng ZG,Xu H,Suo SS,Xu XL,Ni MW,Gu LH,Chen W,Wang LY,Zhao Y,Tian B,Hua YJ
Thu May 19 00:00:00 EDT 2016
Differential Requirements for eIF4E Dose in Normal Development and Cancer.
Cell
Truitt ML,Conn CS,Shi Z,Pang X,Tokuyasu T,Coady AM,Seo Y,Barna M,Ruggero D
Thu Jul 02 00:00:00 EDT 2015
Differential Requirements for eIF4E Dose in Normal Development and Cancer.
Cell
Truitt ML,Conn CS,Shi Z,Pang X,Tokuyasu T,Coady AM,Seo Y,Barna M,Ruggero D
Thu Jul 02 00:00:00 EDT 2015
Estradiol decreases taurine level by reducing cysteine sulfinic acid decarboxylase via the estrogen receptor-α in female mice liver.
American journal of physiology. Gastrointestinal and liver physiology
Ma Q,Zhao J,Cao W,Liu J,Cui S
Sun Feb 15 00:00:00 EST 2015
Estradiol decreases taurine level by reducing cysteine sulfinic acid decarboxylase via the estrogen receptor-α in female mice liver.
American journal of physiology. Gastrointestinal and liver physiology
Ma Q,Zhao J,Cao W,Liu J,Cui S
Sun Feb 15 00:00:00 EST 2015
Sestrin 2 protein regulates platelet-derived growth factor receptor β (Pdgfrβ) expression by modulating proteasomal and Nrf2 transcription factor functions.
The Journal of biological chemistry
Tomasovic A,Kurrle N,Sürün D,Heidler J,Husnjak K,Poser I,Schnütgen F,Scheibe S,Seimetz M,Jaksch P,Hyman A,Weissmann N,von Melchner H
Fri Apr 10 00:00:00 EDT 2015
Sestrin 2 protein regulates platelet-derived growth factor receptor β (Pdgfrβ) expression by modulating proteasomal and Nrf2 transcription factor functions.
The Journal of biological chemistry
Tomasovic A,Kurrle N,Sürün D,Heidler J,Husnjak K,Poser I,Schnütgen F,Scheibe S,Seimetz M,Jaksch P,Hyman A,Weissmann N,von Melchner H
Fri Apr 10 00:00:00 EDT 2015
Sestrin 2 protein regulates platelet-derived growth factor receptor β (Pdgfrβ) expression by modulating proteasomal and Nrf2 transcription factor functions.
The Journal of biological chemistry
Tomasovic A,Kurrle N,Sürün D,Heidler J,Husnjak K,Poser I,Schnütgen F,Scheibe S,Seimetz M,Jaksch P,Hyman A,Weissmann N,von Melchner H
Fri Apr 10 00:00:00 EDT 2015
Dietary flavonoid genistein induces Nrf2 and phase II detoxification gene expression via ERKs and PKC pathways and protects against oxidative stress in Caco-2 cells.
Molecular nutrition & food research
Zhai X,Lin M,Zhang F,Hu Y,Xu X,Li Y,Liu K,Ma X,Tian X,Yao J
Fri Feb 01 00:00:00 EST 2013
Dietary flavonoid genistein induces Nrf2 and phase II detoxification gene expression via ERKs and PKC pathways and protects against oxidative stress in Caco-2 cells.
Molecular nutrition & food research
Zhai X,Lin M,Zhang F,Hu Y,Xu X,Li Y,Liu K,Ma X,Tian X,Yao J
Fri Feb 01 00:00:00 EST 2013
The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense.
Cell reports
Wu H,Xiao Y,Zhang S,Ji S,Wei L,Fan F,Geng J,Tian J,Sun X,Qin F,Jin C,Lin J,Yin ZY,Zhang T,Luo L,Li Y,Song S,Lin SC,Deng X,Camargo F,Avruch J,Chen L,Zhou D
Thu May 30 00:00:00 EDT 2013
The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense.
Cell reports
Wu H,Xiao Y,Zhang S,Ji S,Wei L,Fan F,Geng J,Tian J,Sun X,Qin F,Jin C,Lin J,Yin ZY,Zhang T,Luo L,Li Y,Song S,Lin SC,Deng X,Camargo F,Avruch J,Chen L,Zhou D
Thu May 30 00:00:00 EDT 2013
Fumarates promote cytoprotection of central nervous system cells against oxidative stress via the nuclear factor (erythroid-derived 2)-like 2 pathway.
The Journal of pharmacology and experimental therapeutics
Scannevin RH,Chollate S,Jung MY,Shackett M,Patel H,Bista P,Zeng W,Ryan S,Yamamoto M,Lukashev M,Rhodes KJ
Sun Apr 01 00:00:00 EDT 2012
Fumarates promote cytoprotection of central nervous system cells against oxidative stress via the nuclear factor (erythroid-derived 2)-like 2 pathway.
The Journal of pharmacology and experimental therapeutics
Scannevin RH,Chollate S,Jung MY,Shackett M,Patel H,Bista P,Zeng W,Ryan S,Yamamoto M,Lukashev M,Rhodes KJ
Sun Apr 01 00:00:00 EDT 2012
