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GDF3 Antibody (MA5-52878) in WB
Western Blot analysis of GDF3. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with GDF3 recombinant monoclonal antibody (Product # MA5-52878) with a dilution of 1:5,000, followed by HRP-conjugated goat anti-rabbit secondary antibody with a dilution of 1:20,000. Image was developed using FeQTM ECL Substrate Kit.
Product Details
MA5-52878
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
23GB5540
Immunogen
A synthesized peptide derived from human GDF3 (300-364AA).
Conjugate
Form
Liquid
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
GDF3 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. The function of this protein is unknown, but expression studies suggest it may be involved in regulation of the adult lymphatic and erythroid systems and embryonic development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GDF-3; Growth/differentiation factor 3; VG-1-related protein 2
Gene Aliases: C78318; ecat9; Gdf-3; GDF3; KFS3; MCOP7; MCOPCB6; RGD1564178; UNQ222/PRO248; Vgr-2; Vgr2
UniProt ID: (Human) Q9NR23, (Mouse) Q07104
Entrez Gene ID: (Human) 9573, (Rat) 500311, (Mouse) 14562
skeletal system development
eye development
in utero embryonic development
response to dietary excess
endoderm development
mesoderm development
regulation of cell fate commitment
positive regulation of pathway-restricted SMAD protein phosphorylation
negative regulation of BMP signaling pathway
notochord development
somite rostral/caudal axis specification
growth
regulation of apoptotic process
regulation of MAPK cascade
negative regulation of epidermal cell differentiation
negative regulation of myoblast differentiation
cell development
formation of anatomical boundary
SMAD protein signal transduction
primitive streak formation
signal transduction
biological_process
BMP signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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