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Product Details
H00009573-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
2B10
Immunogen
GDF3 (NP_065685, 265 a.a. approximately 364 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: HRHQLFINFR DLGWHKWIIA PKGFMANYCH GECPFSLTIS LNSSNYAFMQ ALMHAVDPEI PQAVCIPTKL SPISMLYQDN NDNVILRHYE DMVVDECGCG
Target Information
GDF3 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. The function of this protein is unknown, but expression studies suggest it may be involved in regulation of the adult lymphatic and erythroid systems and embryonic development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GDF-3; Growth/differentiation factor 3
Gene Aliases: GDF3; KFS3; MCOP7; MCOPCB6; UNQ222/PRO248
UniProt ID: (Human) Q9NR23
Entrez Gene ID: (Human) 9573
skeletal system development
eye development
in utero embryonic development
response to dietary excess
endoderm development
mesoderm development
regulation of cell fate commitment
positive regulation of pathway-restricted SMAD protein phosphorylation
negative regulation of BMP signaling pathway
notochord development
somite rostral/caudal axis specification
growth
regulation of apoptotic process
regulation of MAPK cascade
negative regulation of epidermal cell differentiation
negative regulation of myoblast differentiation
cell development
formation of anatomical boundary
SMAD protein signal transduction
primitive streak formation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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