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Product Details
PA5-106668
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human GDF7(Accession Q7Z4P5), corresponding to amino acid residues L194-P244.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2854336
Product Specific Information
Antibody detects endogenous levels of total GDF7.
Target Information
This gene encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signalling molecules that regulate diverse processes in growth, repair and embryonic development. In mouse, this gene functions as an inductive signal from the roof plate required for the specification of neuronal identity in the dorsal spinal cord.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GDF-7; Growth/differentiation factor 7
Gene Aliases: BMP12; GDF7
UniProt ID: (Human) Q7Z4P5
Entrez Gene ID: (Human) 151449
axon guidance
positive regulation of pathway-restricted SMAD protein phosphorylation
roof plate formation
spinal cord association neuron differentiation
gland morphogenesis
BMP signaling pathway
epithelial cell differentiation
midbrain development
activin receptor signaling pathway
growth
regulation of apoptotic process
regulation of MAPK cascade
cell fate commitment
positive regulation of neuron differentiation
positive regulation of transcription, DNA-templated
cell development
reproductive structure development
branching morphogenesis of an epithelial tube
forebrain morphogenesis
pathway-restricted SMAD protein phosphorylation
SMAD protein signal transduction
morphogenesis of an epithelial fold
positive regulation of tendon cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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