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Product Details
H00151449-M12
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
4G10
Immunogen
GDF7 (NP_878248.2, 204 a.a. approximately 301 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: VGQRWEAFDV ADAMRRHRRE PRPPRAFCLL LRAVAGPVPS PLALRRLGFG WPGGGGSAAE ERAVLVVSSR TQRKESLFRE IRAQARALGA ALASEPLP
Target Information
This gene encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signalling molecules that regulate diverse processes in growth, repair and embryonic development. In mouse, this gene functions as an inductive signal from the roof plate required for the specification of neuronal identity in the dorsal spinal cord.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GDF-7; Growth/differentiation factor 7
Gene Aliases: BMP12; GDF7
UniProt ID: (Human) Q7Z4P5
Entrez Gene ID: (Human) 151449
axon guidance
positive regulation of pathway-restricted SMAD protein phosphorylation
roof plate formation
spinal cord association neuron differentiation
gland morphogenesis
BMP signaling pathway
epithelial cell differentiation
midbrain development
activin receptor signaling pathway
growth
regulation of apoptotic process
regulation of MAPK cascade
cell fate commitment
positive regulation of neuron differentiation
positive regulation of transcription, DNA-templated
cell development
reproductive structure development
branching morphogenesis of an epithelial tube
forebrain morphogenesis
pathway-restricted SMAD protein phosphorylation
SMAD protein signal transduction
morphogenesis of an epithelial fold
positive regulation of tendon cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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