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Product Details
PA5-102654
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human GDF9(Accession O60383), corresponding to amino acid residues N369-C419.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2852051
Product Specific Information
Antibody detects endogenous levels of total GDF9.
Target Information
GDF9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues.Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. GDF9 is expressed in oocytes and is thought to be required for ovarian folliculogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GDF-9; Growth/differentiation factor 9
Gene Aliases: Gdf-9; GDF9
UniProt ID: (Human) O60383, (Mouse) Q07105
Entrez Gene ID: (Human) 2661, (Rat) 59304, (Mouse) 14566
oocyte growth
transforming growth factor beta receptor signaling pathway
female gamete generation
positive regulation of cell proliferation
positive regulation of pathway-restricted SMAD protein phosphorylation
negative regulation of cell growth
BMP signaling pathway
regulation of apoptotic process
regulation of MAPK cascade
cell development
SMAD protein signal transduction
regulation of progesterone secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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