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This antibody detects mouse GDF-9 in direct ELISAs and both mouse and hamster GDF-9 in Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant mouse (rm) GDF-1, rmGDF-5, rmGDF-6, rmGDF-8, and rmGDF-15 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
GDF9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues.Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. GDF9 is expressed in oocytes and is thought to be required for ovarian folliculogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GDF-9; growth differentiation factor 9; Growth/differentiation factor 9
Gene Aliases: Gdf-9; Gdf9; I79_004327
UniProt ID: (Mouse) Q07105
Entrez Gene ID: (Chinese hamster) 100756618, (Mouse) 14566
Molecular Function:
growth factor
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