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Product Details
PA5-51102
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from the C-terminal region of human GDF-9.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 0.5% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2636550
Product Specific Information
GDF9 Polyclonal Antibody detects endogenous levels of GDF9 protein.
Target Information
GDF9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues.Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. GDF9 is expressed in oocytes and is thought to be required for ovarian folliculogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GDF-9; Growth/differentiation factor 9
Gene Aliases: Gdf-9; GDF9
UniProt ID: (Human) O60383, (Mouse) Q07105
Entrez Gene ID: (Human) 2661, (Rat) 59304, (Mouse) 14566
oocyte growth
transforming growth factor beta receptor signaling pathway
female gamete generation
positive regulation of cell proliferation
positive regulation of pathway-restricted SMAD protein phosphorylation
negative regulation of cell growth
BMP signaling pathway
regulation of apoptotic process
regulation of MAPK cascade
cell development
SMAD protein signal transduction
regulation of progesterone secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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