Product References
Microglial Nogo delays recovery following traumatic brain injury in mice.
Glia
Glotfelty EJ,Hsueh SC,Claybourne Q,Bedolla A,Kopp KO,Wallace T,Zheng B,Luo Y,Karlsson TE,McDevitt RA,Olson L,Greig NH
Published figure using GFAP polyclonal antibody (Product # PA1-10004) in Immunohistochemistry - Free Floating
Sun Oct 01 00:00:00 EDT 2023
Development of a novel bioengineered 3D brain-like tissue for studying primary blast-induced traumatic brain injury.
Journal of neuroscience research
Snapper DM,Reginauld B,Liaudanskaya V,Fitzpatrick V,Kim Y,Georgakoudi I,Kaplan DL,Symes AJ
PA1-10004 was used in Immunohistochemistry-immunofluorescence to develop a 3D in vitro model studying primary blast-induced traumatic brain injury, to discover and characterize relevant biomarkers.
Sun Jan 01 00:00:00 EST 2023
14-3-3γ haploinsufficiency leads to altered dopamine pathway and Parkinson's disease-like motor incoordination in mice.
Molecular brain
Cho E,Park J,Hwang EM,Kim HW,Park JY
PA1-10004 was used in Immunohistochemistry to characterize the molecular and behavioral changes in aged 14-3-3γ heterozygous mice to investigate the role of 14-3-3γ in the brain.
Thu Jan 05 00:00:00 EST 2023
Orai1 calcium channel inhibition prevents progression of chronic pancreatitis.
JCI insight
Szabó V,Csákány-Papp N,Görög M,Madácsy T,Varga Á,Kiss A,Tél B,Jójárt B,Crul T,Dudás K,Bagyánszki M,Bódi N,Ayaydin F,Jee S,Tiszlavicz L,Stauderman KA,Hebbar S,Pallagi P,Maléth J
PA1-10004 was used in Immunohistochemistry-immunofluorescence to suggest that the overactivation of Orai1 is a crucial pathogenetic event in the progression of early CP and that inhibition of Orai1 could prevent the development of end-stage CP.
Mon Jul 10 00:00:00 EDT 2023
4,8-dicarboxyl-8,9-iridoid-1-glycoside Promotes Neural Stem Cell Differentiation Through MeCP2.
Dose-response : a publication of International Hormesis Society
Wang W,Liu Z,Jing B,Mai H,Jiao H,Guan T,Chen D,Kong J,Pan T
PA1-10004 was used in Western Blotting to conclude that knockdown of MeCP2 results in inhibition of NSC differentiation, and the pro-differentiation effect of 388 was mostly abolished.
Sat Aug 13 00:00:00 EDT 2022
Toll-like receptors 2 and 4 differentially regulate the self-renewal and differentiation of spinal cord neural precursor cells.
Stem cell research & therapy
Sanchez-Petidier M,Guerri C,Moreno-Manzano V
Published figure using GFAP polyclonal antibody (Product # PA1-10004) in Immunocytochemistry
Mon Mar 21 00:00:00 EDT 2022
Acute and Delayed Effects of Mechanical Injury on Calcium Homeostasis and Mitochondrial Potential of Primary Neuroglial Cell Culture: Potential Causal Contributions to Post-Traumatic Syndrome.
International journal of molecular sciences
Bakaeva Z,Goncharov M,Krasilnikova I,Zgodova A,Frolov D,Grebenik E,Timashev P,Pinelis V,Surin A
Published figure using GFAP polyclonal antibody (Product # PA1-10004) in Immunocytochemistry
Thu Mar 31 00:00:00 EDT 2022
GFAP-directed Inactivation of Men1 Exploits Glial Cell Plasticity in Favor of Neuroendocrine Reprogramming.
Cellular and molecular gastroenterology and hepatology
Duan S,Sawyer TW,Sontz RA,Wieland BA,Diaz AF,Merchant JL
PA1-10004 was used in Immunohistochemistry-immunofluorescence to show that GFAP-directed Men1 inactivation exploits glial cell plasticity in favor of neuroendocrine differentiation.
Thu Oct 27 00:00:00 EDT 2022
Caspase-dependent apoptosis induces reactivation and gliogenesis of astrocytes in adult mice.
Frontiers in cellular neuroscience
Kim SC,Park JY,Hwang EM
PA1-10004 was used in Immunohistochemistry-immunofluorescence to generate new conditional transgenic mice (cTg) that can induce apoptosis via Cre-dependent active caspase-3 (taCasp3-2A-TEVp) without pathological conditions.
Thu Dec 22 00:00:00 EST 2022
Optic Nerve Head Myelin-Related Protein, GFAP, and Iba1 Alterations in Non-Human Primates With Early to Moderate Experimental Glaucoma.
Investigative ophthalmology & visual science
Chaudhary P,Stowell C,Reynaud J,Gardiner SK,Yang H,Williams G,Williams I,Marsh-Armstrong N,Burgoyne CF
PA1-10004 was used in Immunohistochemistry (Paraffin) to test if optic nerve head (ONH) myelin basic protein (MBP), 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase), glial fibrillary acidic protein (GFAP), and ionized calcium binding adaptor molecule 1 (Iba1) proteins are altered in non-human primate (NHP) early/moderate experimental glaucoma (EG).
Mon Oct 03 00:00:00 EDT 2022
LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions.
Molecular neurodegeneration
Zhao P,Xu Y,Jiang LL,Fan X,Ku Z,Li L,Liu X,Deng M,Arase H,Zhu JJ,Huang TY,Zhao Y,Zhang C,Xu H,Tong Q,Zhang N,An Z
PA1-10004 was used in Immunohistochemistry-immunofluorescence to reveal the molecular mechanisms of LILRB2-mediated inhibition of TREM2 signaling in microglia and demonstrate a novel approach of enhancing TREM2-mediated microglia functions by blocking LILRB2-ligand interactions.
Sat Jun 18 00:00:00 EDT 2022
Cyclin-Dependent Kinase 5 Regulates cPLA2 Activity and Neuroinflammation in Parkinson's Disease.
eNeuro
Paul S,Fatihi S,Sharma S,Kutum R,Fields R,Pant HC,Thukral L,Bk B
PA1-10004 was used in Immunohistochemistry to show that the architecture of the protein changes on each single-point mutation.
Mon Nov 28 00:00:00 EST 2022
The Heart's Pacemaker Mimics Brain Cytoarchitecture and Function: Novel Interstitial Cells Expose Complexity of the SAN.
JACC. Clinical electrophysiology
Bychkov R,Juhaszova M,Calvo-Rubio Barrera M,Donald LAH,Coletta C,Shumaker C,Moorman K,Sirenko ST,Maltsev AV,Sollott SJ,Lakatta EG
PA1-10004 was used in Immunohistochemistry-immunofluorescence to describe the 3-dimensional cytoarchitecture of the mouse SAN, including autonomic innervation, peripheral glial cells, and pacemaker cells.
Sat Oct 01 00:00:00 EDT 2022
Precise control of embolic stroke with magnetized red blood cells in mice.
Communications biology
Jin Y,Shi P,Wang Y,Li J,Zhang J,Zhao X,Ge Y,Huang Y,Guo M,Wang F,Ci B,Xiao X,Gao X,Xu J,Dang B,Ji B,Ge WP,Jia JM
PA1-10004 was used in Immunohistochemistry to provide an animal model mimicking perinatal embolic stroke and imply a potential therapeutic strategy for the treatment of perinatal stroke.
Wed Feb 16 00:00:00 EST 2022
A Strategy for Magnetic and Electric Stimulation to Enhance Proliferation and Differentiation of NPCs Seeded over PLA Electrospun Membranes.
Biomedicines
Cuenca-Ortolá I,Martínez-Rojas B,Moreno-Manzano V,García Castelló M,Monleón Pradas M,Martínez-Ramos C,Más Estellés J
PA1-10004 was used in Immunohistochemistry-immunofluorescence to stimulate to NPCs seeded on aligned poly(lactic acid) nanofibrous scaffolds, using a combination of electric and magnetic stimulation, for in vitro cell conditioning prior transplantation.
Fri Oct 28 00:00:00 EDT 2022
Inflammatory Foreign Body Response Induced by Neuro-Implants in Rat Cortices Depleted of Resident Microglia by a CSF1R Inhibitor and Its Implications.
Frontiers in neuroscience
Sharon A,Jankowski MM,Shmoel N,Erez H,Spira ME
Published figure using GFAP polyclonal antibody (Product # PA1-10004) in Immunohistochemistry
Wed Apr 14 00:00:00 EDT 2021
Inflammatory Foreign Body Response Induced by Neuro-Implants in Rat Cortices Depleted of Resident Microglia by a CSF1R Inhibitor and Its Implications.
Frontiers in neuroscience
Sharon A,Jankowski MM,Shmoel N,Erez H,Spira ME
Published figure using GFAP polyclonal antibody (Product # PA1-10004) in Immunohistochemistry
Wed Apr 14 00:00:00 EDT 2021
AEG-1 Regulates TWIK-1 Expression as an RNA-Binding Protein in Astrocytes.
Brain sciences
Jung HG,Kim A,Kim SC,Park JY,Hwang EM
PA1-10004 was used in Immunocytochemistry to investigate proteins directly regulated by AEG-1 by analyzing their RNA expression patterns in astrocytes transfected with scramble shRNA and AEG-1 shRNA.
Mon Jan 11 00:00:00 EST 2021
AEG-1 Regulates TWIK-1 Expression as an RNA-Binding Protein in Astrocytes.
Brain sciences
Jung HG,Kim A,Kim SC,Park JY,Hwang EM
PA1-10004 was used in Immunocytochemistry to investigate proteins directly regulated by AEG-1 by analyzing their RNA expression patterns in astrocytes transfected with scramble shRNA and AEG-1 shRNA.
Mon Jan 11 00:00:00 EST 2021
Sex differences in the expression of the endocannabinoid system within V1M cortex and PAG of Sprague Dawley rats.
Biology of sex differences
Levine A,Liktor-Busa E,Lipinski AA,Couture S,Balasubramanian S,Aicher SA,Langlais PR,Vanderah TW,Largent-Milnes TM
PA1-10004 was used in Immunohistochemistry to suggest that sex differences exist in the endocannabinoid system in two CNS regions relevant to cortical spreading depression and descending modulatory networks in pain/anxiety.
Mon Nov 08 00:00:00 EST 2021
Sex differences in the expression of the endocannabinoid system within V1M cortex and PAG of Sprague Dawley rats.
Biology of sex differences
Levine A,Liktor-Busa E,Lipinski AA,Couture S,Balasubramanian S,Aicher SA,Langlais PR,Vanderah TW,Largent-Milnes TM
PA1-10004 was used in Immunohistochemistry to suggest that sex differences exist in the endocannabinoid system in two CNS regions relevant to cortical spreading depression and descending modulatory networks in pain/anxiety.
Mon Nov 08 00:00:00 EST 2021
Human-Induced Neural and Mesenchymal Stem Cell Therapy Combined with a Curcumin Nanoconjugate as a Spinal Cord Injury Treatment.
International journal of molecular sciences
Bonilla P,Hernandez J,Giraldo E,González-Pérez MA,Alastrue-Agudo A,Elkhenany H,Vicent MJ,Navarro X,Edel M,Moreno-Manzano V
PA1-10004 was used in Immunocytochemistry to show that the combination of stem cell transplantation and PA-C treatment confers higher neuroprotective effects compared to individual treatments.
Mon May 31 00:00:00 EDT 2021
Human-Induced Neural and Mesenchymal Stem Cell Therapy Combined with a Curcumin Nanoconjugate as a Spinal Cord Injury Treatment.
International journal of molecular sciences
Bonilla P,Hernandez J,Giraldo E,González-Pérez MA,Alastrue-Agudo A,Elkhenany H,Vicent MJ,Navarro X,Edel M,Moreno-Manzano V
PA1-10004 was used in Immunocytochemistry to show that the combination of stem cell transplantation and PA-C treatment confers higher neuroprotective effects compared to individual treatments.
Mon May 31 00:00:00 EDT 2021
Human-Induced Neural and Mesenchymal Stem Cell Therapy Combined with a Curcumin Nanoconjugate as a Spinal Cord Injury Treatment.
International journal of molecular sciences
Bonilla P,Hernandez J,Giraldo E,González-Pérez MA,Alastrue-Agudo A,Elkhenany H,Vicent MJ,Navarro X,Edel M,Moreno-Manzano V
PA1-10004 was used in Immunocytochemistry to show that the combination of stem cell transplantation and PA-C treatment confers higher neuroprotective effects compared to individual treatments.
Mon May 31 00:00:00 EDT 2021
Human-Induced Neural and Mesenchymal Stem Cell Therapy Combined with a Curcumin Nanoconjugate as a Spinal Cord Injury Treatment.
International journal of molecular sciences
Bonilla P,Hernandez J,Giraldo E,González-Pérez MA,Alastrue-Agudo A,Elkhenany H,Vicent MJ,Navarro X,Edel M,Moreno-Manzano V
PA1-10004 was used in Immunocytochemistry to show that the combination of stem cell transplantation and PA-C treatment confers higher neuroprotective effects compared to individual treatments.
Mon May 31 00:00:00 EDT 2021
Ultrastructural Analysis of Neuroimplant-Parenchyma Interfaces Uncover Remarkable Neuroregeneration Along-With Barriers That Limit the Implant Electrophysiological Functions.
Frontiers in neuroscience
Sharon A,Shmoel N,Erez H,Jankowski MM,Friedmann Y,Spira ME
PA1-10004 was used in Immunohistochemistry to demonstrate remarkable regenerative processes including neuritogenesis, axon myelination, synapse formation and capillaries regrowth in contact and around the implant.
Fri Nov 03 00:00:00 EDT 2023
Meningeal Lymphangiogenesis and Enhanced Glymphatic Activity in Mice with Chronically Implanted EEG Electrodes.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Hauglund NL,Kusk P,Kornum BR,Nedergaard M
PA1-10004 was used in Immunohistochemistry to analyse the effects of chronic cranial electrode implantation on glymphatic fluid transport and in provoking structural changes in the meninges and cerebral cortex of male and female mice.
Wed Mar 11 00:00:00 EDT 2020
Optogenetic Modulation of Neural Progenitor Cells Improves Neuroregenerative Potential.
International journal of molecular sciences
Giraldo E,Palmero-Canton D,Martinez-Rojas B,Sanchez-Martin MDM,Moreno-Manzano V
Published figure using GFAP polyclonal antibody (Product # PA1-10004) in Immunocytochemistry
Thu Dec 31 00:00:00 EST 2020
Immunohistological and Ultrastructural Study of the Inflammatory Response to Perforated Polyimide Cortical Implants: Mechanisms Underlying Deterioration of Electrophysiological Recording Quality.
Frontiers in neuroscience
Huang SH,Shmoel N,Jankowski MM,Erez H,Sharon A,Abu-Salah W,Nelken I,Weiss A,Spira ME
PA1-10004 was used in Immunohistochemistry to investigate the mechanisms determining reduced quality of brain electrophysiological recordings.
Sat Oct 03 00:00:00 EDT 2020
Immunohistological and Ultrastructural Study of the Inflammatory Response to Perforated Polyimide Cortical Implants: Mechanisms Underlying Deterioration of Electrophysiological Recording Quality.
Frontiers in neuroscience
Huang SH,Shmoel N,Jankowski MM,Erez H,Sharon A,Abu-Salah W,Nelken I,Weiss A,Spira ME
PA1-10004 was used in Immunohistochemistry to investigate the mechanisms determining reduced quality of brain electrophysiological recordings.
Sat Oct 03 00:00:00 EDT 2020
Astrocyte Infection during Rabies Encephalitis Depends on the Virus Strain and Infection Route as Demonstrated by Novel Quantitative 3D Analysis of Cell Tropism.
Cells
Potratz M,Zaeck L,Christen M,Te Kamp V,Klein A,Nolden T,Freuling CM,Müller T,Finke S
Published figure using GFAP polyclonal antibody (Product # PA1-10004) in Immunocytochemistry
Tue Feb 11 00:00:00 EST 2020
Astrocyte Infection during Rabies Encephalitis Depends on the Virus Strain and Infection Route as Demonstrated by Novel Quantitative 3D Analysis of Cell Tropism.
Cells
Potratz M,Zaeck L,Christen M,Te Kamp V,Klein A,Nolden T,Freuling CM,Müller T,Finke S
Published figure using GFAP polyclonal antibody (Product # PA1-10004) in Immunocytochemistry
Tue Feb 11 00:00:00 EST 2020
Astrocytic AEG-1 regulates expression of TREK-1 under acute hypoxia.
Cell biochemistry and function
Kim A,Jung HG,Kim SC,Choi M,Park JY,Lee SG,Hwang EM
PA1-10004 was used in Immunocytochemistry to show that AEG-1 is a major mediator of hypoxic-regulated TREK-1 expression in normal astrocytes independently of HIF-1α.
Sun Mar 01 00:00:00 EST 2020
Erythrocytic α-synuclein contained in microvesicles regulates astrocytic glutamate homeostasis: a new perspective on Parkinson's disease pathogenesis.
Acta neuropathologica communications
Sheng L,Stewart T,Yang D,Thorland E,Soltys D,Aro P,Khrisat T,Xie Z,Li N,Liu Z,Tian C,Bercow M,Matsumoto J,Zabetian CP,Peskind E,Quinn JF,Shi M,Zhang J
PA1-10004 was used in Immunocytochemistry-immunoflourescence to demonstrate that erythrocyte-derived EVs isolated from Parkinson''s disease patients carried elevated levels of oligomeric α-syn, compared to those from healthy controls.
Wed Jul 08 00:00:00 EDT 2020
CYP46A1 Activation by Efavirenz Leads to Behavioral Improvement without Significant Changes in Amyloid Plaque Load in the Brain of 5XFAD Mice.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Petrov AM,Lam M,Mast N,Moon J,Li Y,Maxfield E,Pikuleva IA
PA1-10004 was used in Western Blotting to represent a model of behavioral and other improvements independent of the levels of the amyloid peptides and provides insight into potential outcomes of the future clinical trial.
Mon Jul 01 00:00:00 EDT 2019
Organized Neurogenic-Niche-Like Pinwheel Structures Discovered in Spinal Cord Tissue-Derived Neurospheres.
Frontiers in cell and developmental biology
Rodriguez-Jimenez FJ,Clemente E,Moreno-Manzano V,Erceg S
PA1-10004 was used in Immunocytochemistry to suggest that the ratio of ciliated astrocytes to ependymal cells plays a crucial role in the correct formation of the pinwheel structures in spinal cord tissue-derived neurospheres in vitro.
Thu Oct 01 00:00:00 EDT 2020
Neutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis.
Nature communications
Mohanty T,Fisher J,Bakochi A,Neumann A,Cardoso JFP,Karlsson CAQ,Pavan C,Lundgaard I,Nilson B,Reinstrup P,Bonnevier J,Cederberg D,Malmström J,Bentzer P,Linder A
PA1-10004 was used in Immunohistochemistry to show neutrophil extracellular traps in the cerebrospinal fluid of patients with pneumococcal meningitis and their absence in other forms of meningitis with neutrophil influx.
Wed Apr 10 00:00:00 EDT 2019
Implication of Melanopsin and Trigeminal Neural Pathways in Blue Light Photosensitivity in vivo.
Frontiers in neuroscience
Marek V,Reboussin E,Dégardin-Chicaud J,Charbonnier A,Domínguez-López A,Villette T,Denoyer A,Baudouin C,Réaux-Le Goazigo A,Mélik Parsadaniantz S
PA1-10004 was used in Immunohistochemistry-immunofluorescence to study the role of various neural pathways in blue-light aversion.
Thu Oct 12 00:00:00 EDT 2023
Mechanisms that minimize retinal impact of apolipoprotein E absence.
Journal of lipid research
Saadane A,Petrov A,Mast N,El-Darzi N,Dao T,Alnemri A,Song Y,Dunaief JL,Pikuleva IA
PA1-10004 was used in Immunohistochemistry to show apolipoprotein APOA1, APOA4, and APOJ-containing particles still transport cholesterol into the intraretinal space in APOE absence thus minimizing retinal impact.
Sat Dec 01 00:00:00 EST 2018
Voluntary running enhances glymphatic influx in awake behaving, young mice.
Neuroscience letters
von Holstein-Rathlou S,Petersen NC,Nedergaard M
PA1-10004 was used in Immunohistochemistry to show that daily running increases CSF flux in widespread areas of the mouse brain, which may contribute to the pro-cognitive effects of exercise.
Mon Jan 01 00:00:00 EST 2018
Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo.
Cell stem cell
Guimarães-Camboa N,Cattaneo P,Sun Y,Moore-Morris T,Gu Y,Dalton ND,Rockenstein E,Masliah E,Peterson KL,Stallcup WB,Chen J,Evans SM
PA1-10004 was used in immunohistochemistry to report that Tbx18 selectively marks pericytes and vascular smooth muscle cells
Thu Mar 02 00:00:00 EST 2017
The astrocytic response to the dopaminergic denervation of the striatum.
Journal of neurochemistry
Morales I,Sanchez A,Rodriguez-Sabate C,Rodriguez M
PA1-10004 was used in Immunocytochemistry and Immunohistochemistry to help to understand the role of striatal astrocytes during the dopaminergic denervation which characterizes the first stages of PD.
Sat Oct 01 00:00:00 EDT 2016
The astrocytic response to the dopaminergic denervation of the striatum.
Journal of neurochemistry
Morales I,Sanchez A,Rodriguez-Sabate C,Rodriguez M
PA1-10004 was used in Immunocytochemistry and Immunohistochemistry to help to understand the role of striatal astrocytes during the dopaminergic denervation which characterizes the first stages of PD.
Sat Oct 01 00:00:00 EDT 2016
PI3K/AKT pathway regulates E-cadherin and Desmoglein 2 in aggressive prostate cancer.
Cancer medicine
Barber AG,Castillo-Martin M,Bonal DM,Jia AJ,Rybicki BA,Christiano AM,Cordon-Cardo C
Published figure using GFAP polyclonal antibody (Product # PA1-10004) in Immunocytochemistry
Sat Aug 01 00:00:00 EDT 2015
Localization and behaviors in null mice suggest that ASIC1 and ASIC2 modulate responses to aversive stimuli.
Genes, brain, and behavior
Price MP,Gong H,Parsons MG,Kundert JR,Reznikov LR,Bernardinelli L,Chaloner K,Buchanan GF,Wemmie JA,Richerson GB,Cassell MD,Welsh MJ
PA1-10004 was used in immunohistochemistry to study the role of ASIC1 and ASIC2 channels in the defensive response to aversive stimuli
Sat Feb 01 00:00:00 EST 2014
Intranasal delivery of caspase-9 inhibitor reduces caspase-6-dependent axon/neuron loss and improves neurological function after stroke.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Akpan N,Serrano-Saiz E,Zacharia BE,Otten ML,Ducruet AF,Snipas SJ,Liu W,Velloza J,Cohen G,Sosunov SA,Frey WH,Salvesen GS,Connolly ES,Troy CM
PA1-10004 was used in immunohistochemistry to investigate the therapeutic effect of caspase-9 inhibitor on ischemic stroke
Wed Jun 15 00:00:00 EDT 2011
