Product References
Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex-mediated STAT1 downregulation.
The Journal of experimental medicine
Zhan X,Guo S,Li Y,Ran H,Huang H,Mi L,Wu J,Wang X,Xiao D,Chen L,Li D,Zhang S,Yan X,Yu Y,Li T,Han Q,He K,Cui J,Li T,Zhou T,Rich JN,Bao S,Zhang X,Li A,Man J
A-21282 was used in Immunocytochemistry-immunoflourescence to demonstrate that glioma stem-like cells (GSCs) evade type I IFN suppression through downregulation of STAT1 to initiate tumor growth under inhospitable conditions.
Mon May 04 00:00:00 EDT 2020
Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex-mediated STAT1 downregulation.
The Journal of experimental medicine
Zhan X,Guo S,Li Y,Ran H,Huang H,Mi L,Wu J,Wang X,Xiao D,Chen L,Li D,Zhang S,Yan X,Yu Y,Li T,Han Q,He K,Cui J,Li T,Zhou T,Rich JN,Bao S,Zhang X,Li A,Man J
A-21282 was used in Immunocytochemistry-immunoflourescence to demonstrate that glioma stem-like cells (GSCs) evade type I IFN suppression through downregulation of STAT1 to initiate tumor growth under inhospitable conditions.
Mon May 04 00:00:00 EDT 2020
Biological Characterization and Therapeutics for Subscalp Recurrent in Intracranial Glioblastoma.
OncoTargets and therapy
Zhang J,Fang S,Song W,Zhang B,Fan W,Jin G,Liu F
Published figure using GFAP monoclonal antibody (Product # A-21282) in Immunocytochemistry
Sun Apr 17 00:00:00 EDT 2022
Biological Characterization and Therapeutics for Subscalp Recurrent in Intracranial Glioblastoma.
OncoTargets and therapy
Zhang J,Fang S,Song W,Zhang B,Fan W,Jin G,Liu F
Published figure using GFAP monoclonal antibody (Product # A-21282) in Immunocytochemistry
Sun Apr 17 00:00:00 EDT 2022
Tau interactome analyses in CRISPR-Cas9 engineered neuronal cells reveal ATPase-dependent binding of wild-type but not P301L Tau to non-muscle myosins.
Scientific reports
Wang X,Williams D,Müller I,Lemieux M,Dukart R,Maia IBL,Wang H,Woerman AL,Schmitt-Ulms G
A-21282 was used in Immunocytochemistry to show ATPase-dependent binding of Tau to non-muscle myosins is occluded in P301L Tau mutants.
Thu Nov 07 00:00:00 EST 2019
Longitudinal Functional Assessment of Brain Injury Induced by High-Intensity Ultrasound Pulse Sequences.
Scientific reports
Ye M,Solarana K,Rafi H,Patel S,Nabili M,Liu Y,Huang S,Fisher JAN,Krauthamer V,Myers M,Welle C
A-21282 was used in Immunohistochemistry to assess the neuroinflammatory response, behavioural effects and brain micro-electrocorticographic signals in mice following exposure to a train of transcranial pulses above normal clinical parameters.
Tue Oct 29 00:00:00 EDT 2019
SOX2-Dependent Transcription in Clock Neurons Promotes the Robustness of the Central Circadian Pacemaker.
Cell reports
Cheng AH,Bouchard-Cannon P,Hegazi S,Lowden C,Fung SW,Chiang CK,Ness RW,Cheng HM
A-21282 was used in Immunohistochemistry-immunofluorescence to show that by defining the transcriptional landscape within SCN neurons, SOX2 enables the generation of robust, entrainable circadian rhythms that accurately reflect environmental time.
Tue Mar 19 00:00:00 EDT 2019
The Spectrin-Actin-Based Periodic Cytoskeleton as a Conserved Nanoscale Scaffold and Ruler of the Neural Stem Cell Lineage.
Cell reports
Hauser M,Yan R,Li W,Repina NA,Schaffer DV,Xu K
A-21282 was used in Immunocytochemistry-immunoflourescence to resolve the spectrin-actin-based membrane cytoskeleton of neural stem cells (NSCs) and NSC-derived neurons, astrocytes, and oligodendrocytes.
Tue Aug 07 00:00:00 EDT 2018
Astrocytes promote progression of breast cancer metastases to the brain via a KISS1-mediated autophagy.
Autophagy
Kaverina N,Borovjagin AV,Kadagidze Z,Baryshnikov A,Baryshnikova M,Malin D,Ghosh D,Shah N,Welch DR,Gabikian P,Karseladze A,Cobbs C,Ulasov IV
Published figure using GFAP monoclonal antibody (Product # A-21282) in Immunofluorescence
Tue Jun 04 00:00:00 EDT 2019
Astrocytes promote progression of breast cancer metastases to the brain via a KISS1-mediated autophagy.
Autophagy
Kaverina N,Borovjagin AV,Kadagidze Z,Baryshnikov A,Baryshnikova M,Malin D,Ghosh D,Shah N,Welch DR,Gabikian P,Karseladze A,Cobbs C,Ulasov IV
Published figure using GFAP monoclonal antibody (Product # A-21282) in Immunofluorescence
Tue Jun 04 00:00:00 EDT 2019
Transplantation of neurons derived from human iPS cells cultured on collagen matrix into guinea-pig cochleae.
Journal of tissue engineering and regenerative medicine
Ishikawa M,Ohnishi H,Skerleva D,Sakamoto T,Yamamoto N,Hotta A,Ito J,Nakagawa T
A-21282 was used in immunocytochemistry evaluate the efficacy of a neural induction method for human induced pluripotent stem cells and transplant these cells into guinea-pig cochleae for replacement of spiral ganglion neurons
Thu Jun 01 00:00:00 EDT 2017
Generation of Mouse Haploid Somatic Cells by Small Molecules for Genome-wide Genetic Screening.
Cell reports
He ZQ,Xia BL,Wang YK,Li J,Feng GH,Zhang LL,Li YH,Wan HF,Li TD,Xu K,Yuan XW,Li YF,Zhang XX,Zhang Y,Wang L,Li W,Zhou Q
A-21282 was used in Flow cytometry to demonstrate that the spontaneous diploidisation of haploid embryonic stem cells happens in metaphase due to mitotic slippage.
Tue Aug 29 00:00:00 EDT 2017
Genetic Ablation of Soluble TNF Does Not Affect Lesion Size and Functional Recovery after Moderate Spinal Cord Injury in Mice.
Mediators of inflammation
Ellman DG,Degn M,Lund MC,Clausen BH,Novrup HG,Flæng SB,Jørgensen LH,Suntharalingam L,Svenningsen ÅF,Brambilla R,Lambertsen KL
A21282 was used in immunohistochemistry - paraffin section to examine the effect of genetic ablation of soluble tumor necrosis factor on traumatic spinal cord injury
Fri Jun 16 00:00:00 EDT 2017
Status epilepticus stimulates NDEL1 expression via the CREB/CRE pathway in the adult mouse brain.
Neuroscience
Choi YS,Lee B,Hansen KF,Aten S,Horning P,Wheaton KL,Impey S,Hoyt KR,Obrietan K
A21282 was used in immunohistochemistry to investigate the effects of inducible NDEL1 expression in the adult mouse forebrain
Wed Sep 07 00:00:00 EDT 2016
The autophagic- lysosomal pathway determines the fate of glial cells under manganese- induced oxidative stress conditions.
Free radical biology & medicine
Gorojod RM,Alaimo A,Porte Alcon S,Pomilio C,Saravia F,Kotler ML
A-21282 was used in immunohistochemistry (free floating) to report that autophagy is activated to counteract the harmful effect caused by manganese.
Thu Oct 01 00:00:00 EDT 2015
NFIX Regulates Proliferation and Migration Within the Murine SVZ Neurogenic Niche.
Cerebral cortex (New York, N.Y. : 1991)
Heng YH,Zhou B,Harris L,Harvey T,Smith A,Horne E,Martynoga B,Andersen J,Achimastou A,Cato K,Richards LJ,Gronostajski RM,Yeo GS,Guillemot F,Bailey TL,Piper M
A-21282 was used in immunohistochemistry (free floating) to use Nfix(-/-) mice to study development of the nervous system.
Thu Oct 01 00:00:00 EDT 2015
VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells.
The Journal of experimental medicine
Schneider-Hohendorf T,Rossaint J,Mohan H,Böning D,Breuer J,Kuhlmann T,Gross CC,Flanagan K,Sorokin L,Vestweber D,Zarbock A,Schwab N,Wiendl H
A-21282 was used in immunohistochemistry - paraffin section to characterize VLA-4 blockade and promotion of differential routes into human CNS involving MCAM-adhesion of TH17 cells and PSGL-1 rolling of T cells
Mon Aug 25 00:00:00 EDT 2014
A comparison of neuroinflammation to implanted microelectrodes in rat and mouse models.
Biomaterials
Potter-Baker KA,Ravikumar M,Burke AA,Meador WD,Householder KT,Buck AC,Sunil S,Stewart WG,Anna JP,Tomaszewski WH,Capadona JR
A-21282 was used in Immunohistochemistry to compare neuroinflammation following microelectrode implantation between rat and mouse models.
Tue Jul 01 00:00:00 EDT 2014
Curcumin-releasing mechanically adaptive intracortical implants improve the proximal neuronal density and blood-brain barrier stability.
Acta biomaterialia
Potter KA,Jorfi M,Householder KT,Foster EJ,Weder C,Capadona JR
A-21282 was used in immunohistochemistry to test if using implant softening and antioxidant release reduces neuroinflammation
Thu May 01 00:00:00 EDT 2014
Primary cultured astrocytes from old rats are capable to activate the Nrf2 response against MPP+ toxicity after tBHQ pretreatment.
Neurobiology of aging
Alarcón-Aguilar A,Luna-López A,Ventura-Gallegos JL,Lazzarini R,Galván-Arzate S,González-Puertos VY,Morán J,Santamaría A,Königsberg M
A-21282 was used in western blot to test if cortical astrocytes derived from old rats respond to tertbuthyl-hydroquinene pretreatment and promote an antioxidant rich environment
Fri Aug 01 00:00:00 EDT 2014
Central but not systemic administration of XPro1595 is therapeutic following moderate spinal cord injury in mice.
Journal of neuroinflammation
Novrup HG,Bracchi-Ricard V,Ellman DG,Ricard J,Jain A,Runko E,Lyck L,Yli-Karjanmaa M,Szymkowski DE,Pearse DD,Lambertsen KL,Bethea JR
A-21282 was used in immunocytochemistry to elucidate the contribution of soluble TNF and transmembrane-associated TNF to the development of the lesion in the central nervous system
Wed Sep 10 00:00:00 EDT 2014
Central but not systemic administration of XPro1595 is therapeutic following moderate spinal cord injury in mice.
Journal of neuroinflammation
Novrup HG,Bracchi-Ricard V,Ellman DG,Ricard J,Jain A,Runko E,Lyck L,Yli-Karjanmaa M,Szymkowski DE,Pearse DD,Lambertsen KL,Bethea JR
A-21282 was used in immunocytochemistry to elucidate the contribution of soluble TNF and transmembrane-associated TNF to the development of the lesion in the central nervous system
Wed Sep 10 00:00:00 EDT 2014
Flexibilide obtained from cultured soft coral has anti-neuroinflammatory and analgesic effects through the upregulation of spinal transforming growth factor-β1 in neuropathic rats.
Marine drugs
Chen NF,Huang SY,Lu CH,Chen CL,Feng CW,Chen CH,Hung HC,Lin YY,Sung PJ,Sung CS,Yang SN,Wang HM,Chang YC,Sheu JH,Chen WF,Wen ZH
A-21282 was used in immunohistochemistry - frozen section to elucidate the role of flexibilide from cultured soft coral and its analgesic and anti-neuroinflammatory effects through upregulation of spinal transofrming growth factor-beta1 in neuropathic rat
Fri Jun 27 00:00:00 EDT 2014
The effect of resveratrol on neurodegeneration and blood brain barrier stability surrounding intracortical microelectrodes.
Biomaterials
Potter KA,Buck AC,Self WK,Callanan ME,Sunil S,Capadona JR
A-21282 was used in immunohistochemistry to find a biological mechanism which mediates neuroinflammation.
Sun Sep 01 00:00:00 EDT 2013
The mood stabilizer valproate activates human FGF1 gene promoter through inhibiting HDAC and GSK-3 activities.
Journal of neurochemistry
Kao CY,Hsu YC,Liu JW,Lee DC,Chung YF,Chiu IM
A-21282 was used in western blot to
Mon Jul 01 00:00:00 EDT 2013
TGF-β1 attenuates spinal neuroinflammation and the excitatory amino acid system in rats with neuropathic pain.
The journal of pain
Chen NF,Huang SY,Chen WF,Chen CH,Lu CH,Chen CL,Yang SN,Wang HM,Wen ZH
A-21282 was used in immunohistochemistry (frozen) to study the antinociceptive effects of TGF-β1 on chronic constriction injury-induced neuropathic pain in rats.
Sun Dec 01 00:00:00 EST 2013
Novel MeCP2 isoform-specific antibody reveals the endogenous MeCP2E1 expression in murine brain, primary neurons and astrocytes.
PloS one
Zachariah RM,Olson CO,Ezeonwuka C,Rastegar M
Published figure using GFAP monoclonal antibody (Product # A-21282) in Immunofluorescence
Thu May 30 00:00:00 EDT 2013
Sinularin from indigenous soft coral attenuates nociceptive responses and spinal neuroinflammation in carrageenan-induced inflammatory rat model.
Marine drugs
Huang SY,Chen NF,Chen WF,Hung HC,Lee HP,Lin YY,Wang HM,Sung PJ,Sheu JH,Wen ZH
A-21282 was used in immunohistochemistry to report that systemic sinularin exerts analgesic effects at the behavioral and spinal levels
Sat Sep 01 00:00:00 EDT 2012
Prophylactic and therapeutic targeting of the neurokinin-1 receptor limits neuroinflammation in a murine model of pneumococcal meningitis.
Journal of immunology (Baltimore, Md. : 1950)
Chauhan VS,Kluttz JM,Bost KL,Marriott I
A-21282 was used in flow cytometry to study SP/NK-1R targeting as a treatment option fro microbe induced neuroinflammation.
Wed Jun 15 00:00:00 EDT 2011
House-dust mite allergen and ozone exposure decreases histamine H3 receptors in the brainstem respiratory nuclei.
Toxicology and applied pharmacology
Sekizawa S,Bechtold AG,Tham RC,Kott KS,Hyde DM,Joad JP,Bonham AC
A-21282 was used in immunohistochemistry to test if airway allergic diseases are associated with altered histamine H3 receptor expression in the nucleus tractus solitarius and caudal spinal trigeminal nucleus in the lung
Wed Sep 15 00:00:00 EDT 2010
Toll-like receptor 2 and facial motoneuron survival after facial nerve axotomy.
Neuroscience letters
Wainwright DA,Xin J,Mesnard NA,Sanders VM,Jones KJ
A-21282 was used in immunohistochemistry - frozen section to explore role of TLR2 in the facial motoneuron response to axotomy
Fri Feb 26 00:00:00 EST 2010
Distribution of leptin-sensitive cells in the postnatal and adult mouse brain.
The Journal of comparative neurology
Caron E,Sachot C,Prevot V,Bouret SG
A-21282 was used in immunohistochemistry to identify leptin-sensitive cells in the postnatal and adult rodent brain
Mon Feb 15 00:00:00 EST 2010
Intraspinal cord delivery of IGF-I mediated by adeno-associated virus 2 is neuroprotective in a rat model of familial ALS.
Neurobiology of disease
Franz CK,Federici T,Yang J,Backus C,Oh SS,Teng Q,Carlton E,Bishop KM,Gasmi M,Bartus RT,Feldman EL,Boulis NM
A-21282 was used in immunohistochemistry - frozen section to assess the efficacy of intraspinal cord injection of CERE-130 on motor neurons and preservation of neuromuscular function
Sun Mar 01 00:00:00 EST 2009
Effects of facial nerve axotomy on Th2- and Th1-associated chemokine expression in the facial motor nucleus of wild-type and presymptomatic mSOD1 mice.
Journal of neuroimmunology
Wainwright DA,Xin J,Mesnard NA,Politis CM,Sanders VM,Jones KJ
A-21282 was used in immunohistochemistry - frozen section to investigate the role of CXCL11 in facial motoneuron survival
Mon Nov 30 00:00:00 EST 2009
Prokineticin receptor 2 expression identifies migrating neuroblasts and their subventricular zone transient-amplifying progenitors in adult mice.
The Journal of comparative neurology
Puverel S,Nakatani H,Parras C,Soussi-Yanicostas N
A-21282 was used in immunocytochemistry and immunohistochemistry to study the expression of prokineticin receptor 2 and the identification of migrating neuroblasts in adult mice
Sat Jan 10 00:00:00 EST 2009
MECP2 isoform-specific vectors with regulated expression for Rett syndrome gene therapy.
PloS one
Rastegar M,Hotta A,Pasceri P,Makarem M,Cheung AY,Elliott S,Park KJ,Adachi M,Jones FS,Clarke ID,Dirks P,Ellis J
A-21282 was used in immunocytochemistry to develop viral vectors to treat patients with Rett Syndrome
Thu Aug 27 00:00:00 EDT 2009
Exacerbation of facial motoneuron loss after facial nerve axotomy in CCR3-deficient mice.
ASN neuro
Wainwright DA,Xin J,Mesnard NA,Beahrs TR,Politis CM,Sanders VM,Jones KJ
A-21282 was used in immunohistochemistry (frozen) to assess if Th2-associated chemokine receptors increase in the facial motor nucleus after facial nerve axotomy.
Fri Dec 11 00:00:00 EST 2009
Basic fibroblast growth factor impact on retinoblastoma progression and survival.
Investigative ophthalmology & visual science
Cebulla CM,Jockovich ME,Piña Y,Boutrid H,Alegret A,Kulak A,Hackam AS,Bhattacharya SK,Feuer WJ,Murray TG
A-21282 was used in immunohistochemistry - frozen section to assess basic fibroblast growth factor as a growth and chemoresistance factor in retinoblastoma
Mon Dec 01 00:00:00 EST 2008
Attenuation of astroglial reactivity by interleukin-10.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Balasingam V,Yong VW
A-21282 was used in flow cytometry and immunohistochemistry to test if astroglial reactivity is attenuated by the application of interleukin-10 to the site of corticectomy
Wed May 01 00:00:00 EDT 1996
