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Product Details
PA5-57851
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GFM2. Recombinant protein control fragment (Product #RP-96919).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2641964
Product Specific Information
Immunogen sequence: TSTTMISACV SRCVQKALKK ADKQVLEPLM NLEVTVARDY LSPVLADLAQ RRGNIQEIQT RQDNKVVIGF VPLAEIMGYS T
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 91%.
Target Information
GFM2 is involved in mitochondrial translation, which is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. In Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. This gene encodes one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in at least three transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EF-G2mt; Elongation factor G 2, mitochondrial; Elongation factor G2; G elongation factor; G elongation factor, mitochondrial 2; GFM2; hEFG2; mEF-G 2; mitochondrial elongation factor G2; mitochondrial ribosome recycling factor 2; Ribosome-releasing factor 2, mitochondrial; RRF2mt
Gene Aliases: EF-G2mt; EFG2; GFM2; hEFG2; mEF-G 2; MRRF2; MST027; MSTP027; RRF2; RRF2mt
UniProt ID: (Human) Q969S9
Entrez Gene ID: (Human) 84340
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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