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Immunogen sequence: ETSEGVSLQL GNTKDFIISF DLKFLTNGSV SVVLETTEKN QLFTIHYVSN AQLIAFKERD IYYGIGPRTS WSTVTRDLVT DLRKGVGLSN TKAVKPTKIM PKKVVRLI
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 94%.
Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acid residues, both in maturing heparan sulfate (HS) and heparin chains. This is important for further modifications that determine the specificity of interactions between these glycosaminoglycans and proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: D-glucuronyl C5-epimerase; glucuronyl C5-epimerase; Heparan sulfate C5-epimerase; heparan sulfate epimerase; heparin/heparan sulfate-glucuronic acid C5-epimerase; Heparin/heparan sulfate:glucuronic acid C5-epimerase; Heparosan-N-sulfate-glucuronate 5-epimerase; Hsepi; UDP-glucuronic acid epimerase
Gene Aliases: GLCE; HSEPI; KIAA0836
UniProt ID: (Human) O94923
Entrez Gene ID: (Human) 26035
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