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GLP1R Antibody (PA5-97788) in WB
Western Blot analysis of GLP1R using a GLP1R Polyclonal antibody (Product # PA5-97788) at a concentration of 3 µg/mL. Positive WB detected in: Mouse spleen tissue, Mouse lung tissue, Mouse stomach tissue. A secondary Goat polyclonal antibody to rabbit IgG was applied at a 1:50,000 dilution. Observed band size: 54 kDa.
Product Details
PA5-97788
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Mouse Glucagon-like peptide 1 receptor protein (22-145AA)
Conjugate
Form
Liquid
Concentration
3 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_2812403
Target Information
Glucagon-like peptide-1(9-36)amide and GLP-1(9-37) are the forms of GLP-1 that result from the rapid degradation of the active forms of the peptide (GLP-1(7-36)amide and GLP-1(7-37)) by the enzyme dipeptidyl peptidase-IV (DPP-IV, also known as CD26 or adenosine deaminase binding protein). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GLP-1 receptor; GLP-1-R; GLP-I receptor; Glucagon-like peptide 1 receptor
Gene Aliases: GLP-1R; Glp1r; GLP1Rc
UniProt ID: (Mouse) O35659
Entrez Gene ID: (Mouse) 14652
response to stress
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
learning or memory
memory
feeding behavior
regulation of heart contraction
positive regulation of cell proliferation
associative learning
response to glucose
cAMP-mediated signaling
insulin secretion
positive regulation of insulin secretion
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
positive regulation of cell differentiation
positive regulation of blood pressure
positive regulation of heart contraction
positive regulation of transcription from RNA polymerase II promoter
hormone secretion
release of sequestered calcium ion into cytosol
regulation of calcium ion transport
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